×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Neoplasms
0.700
GeneticVariation
CLINVAR
Impact of microsatellite testing and mismatch repair protein expression on the clinical interpretation of genetic testing in hereditary non-polyposis colorectal cancer.
12200596
2002
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Neoplasms
0.700
GeneticVariation
CLINVAR
Cancer Susceptibility Gene Mutations in Individuals With Colorectal Cancer.
28135145
2017
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Neoplasms
0.700
GeneticVariation
CLINVAR
A high incidence of MSH6 mutations in Amsterdam criteria II-negative families tested in a diagnostic setting.
18625694
2008
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Neoplasms
0.700
GeneticVariation
CLINVAR
Microsatellite instability and mutation analysis among southern Italian patients with colorectal carcinoma: detection of different alterations accounting for MLH1 and MSH2 inactivation in familial cases.
14504054
2003
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Neoplasms
0.700
GeneticVariation
CLINVAR
The interaction of the human MutL homologues in hereditary nonpolyposis colon cancer.
10037723
1999
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Neoplasms
0.700
GeneticVariation
LHGDN
Identification and characterization of genomic rearrangements of MSH2 and MLH1 in Lynch syndrome (HNPCC) by novel techniques.
12938096
2003
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Neoplasms
0.700
GeneticVariation
CLINVAR
Impact of genetic counseling and DNA testing on individuals with colorectal cancer with a positive family history: a population-based study.
16379545
2005
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Neoplasms
0.700
GeneticVariation
CLINVAR
Conventional and tissue microarray immunohistochemical expression analysis of mismatch repair in hereditary colorectal tumors.
12547705
2003
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Neoplasms
0.700
GeneticVariation
CLINVAR
Functional analysis of human MLH1 variants using yeast and in vitro mismatch repair assays.
17510385
2007
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Neoplasms
0.700
GeneticVariation
CLINVAR
Clinical features and mismatch repair genes analyses of Chinese suspected hereditary non-polyposis colorectal cancer: a cost-effective screening strategy proposal.
18307539
2008
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Neoplasms
0.700
GeneticVariation
LHGDN
Characterization of hMLH1 and hMSH2 gene dosage alterations in Lynch syndrome patients.
16143124
2005
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Neoplasms
0.700
GeneticVariation
CLINVAR
Identification of Lynch syndrome mutations in the MLH1-PMS2 interface that disturb dimerization and mismatch repair.
20533529
2010
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Neoplasms
0.700
GeneticVariation
CLINVAR
Mutation analysis of hMSH2 and hMLH1 in colorectal cancer patients in India.
15345113
2004
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Neoplasms
0.700
GeneticVariation
CLINVAR
Integrative analysis of hereditary nonpolyposis colorectal cancer: the contribution of allele-specific expression and other assays to diagnostic algorithms.
24278394
2013
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Neoplasms
0.700
GeneticVariation
LHGDN
Clinical features and hMSH2/hMLH1 germ-line mutations in Chinese patients with hereditary nonpolyposis colorectal cancer.
18713544
2008
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Neoplasms
0.700
GeneticVariation
CLINVAR
A large fraction of unclassified variants of the mismatch repair genes MLH1 and MSH2 is associated with splicing defects.
18561205
2008
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Neoplasms
0.700
GeneticVariation
CLINVAR
Functional testing strategy for coding genetic variants of unclear significance in MLH1 in Lynch syndrome diagnosis.
25477341
2015
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Neoplasms
0.700
GeneticVariation
CLINVAR
Functional significance and clinical phenotype of nontruncating mismatch repair variants of MLH1.
16083711
2005
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Neoplasms
0.700
GeneticVariation
CLINVAR
Comprehensive functional assessment of MLH1 variants of unknown significance.
22736432
2012
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Neoplasms
0.700
GeneticVariation
CLINVAR
Classification of mismatch repair gene missense variants with PON-MMR.
22290698
2012
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Neoplasms
0.700
GeneticVariation
LHGDN
Different molecular mechanisms underlie genomic deletions in the MLH1 Gene.
12402334
2002
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Neoplasms
0.700
GeneticVariation
CLINVAR
Conversion analysis for mutation detection in MLH1 and MSH2 in patients with colorectal cancer.
15713769
2005
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Neoplasms
0.700
GeneticVariation
LHGDN
Chromoendoscopic colonoscopy for detecting preneoplastic lesions in hereditary nonpolyposis colorectal cancer syndrome.
16234028
2005
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Neoplasms
0.700
GeneticVariation
LHGDN
Clinicopathological and molecular genetic analysis of HNPCC in China.
15786548
2005
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Neoplasms
0.700
GeneticVariation
CLINVAR
Germline mutations of the hMLH1 and hMSH2 mismatch repair genes in Belgian hereditary nonpolyposis colon cancer (HNPCC) patients.
16736289
2006