×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Neoplasms
0.700
CausalMutation
CLINVAR
Comparison between universal molecular screening for Lynch syndrome and revised Bethesda guidelines in a large population-based cohort of patients with colorectal cancer.
21868491
2012
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Neoplasms
0.700
GeneticVariation
CLINVAR
Impact of microsatellite testing and mismatch repair protein expression on the clinical interpretation of genetic testing in hereditary non-polyposis colorectal cancer.
12200596
2002
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Neoplasms
0.700
CausalMutation
CLINVAR
The frequency of Muir-Torre syndrome among Lynch syndrome families.
18270343
2008
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Neoplasms
0.700
CausalMutation
CLINVAR
Genetic counseling in a Navajo hereditary nonpolyposis colorectal cancer kindred.
8630936
1996
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Neoplasms
0.700
CausalMutation
CLINVAR
Two novel mutations in hMLH1 gene in Iranian hereditary non-polyposis colorectal cancer patients.
21901500
2012
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Neoplasms
0.700
CausalMutation
CLINVAR
Identification of Lynch syndrome mutations in the MLH1-PMS2 interface that disturb dimerization and mismatch repair.
20533529
2010
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Neoplasms
0.700
GeneticVariation
CLINVAR
Cancer Susceptibility Gene Mutations in Individuals With Colorectal Cancer.
28135145
2017
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Neoplasms
0.700
CausalMutation
CLINVAR
Redundant DNA methylation in colorectal cancers of Lynch-syndrome patients.
18618713
2008
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Neoplasms
0.700
GeneticVariation
CLINVAR
A high incidence of MSH6 mutations in Amsterdam criteria II-negative families tested in a diagnostic setting.
18625694
2008
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Neoplasms
0.700
CausalMutation
CLINVAR
Microsatellite instability and novel mismatch repair gene mutations in northern Chinese population with hereditary non-polyposis colorectal cancer.
17054581
2006
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Neoplasms
0.700
CausalMutation
CLINVAR
Germline, somatic and epigenetic events underlying mismatch repair deficiency in colorectal and HNPCC-related cancers.
12386821
2002
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Neoplasms
0.700
CausalMutation
CLINVAR
Homozygosity at variant MLH1 can lead to secondary mutation in NF1, neurofibromatosis type I and early onset leukemia.
17889038
2008
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Neoplasms
0.700
CausalMutation
CLINVAR
The effect of genetic background on the function of Saccharomyces cerevisiae mlh1 alleles that correspond to HNPCC missense mutations.
17210669
2007
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Neoplasms
0.700
GeneticVariation
CLINVAR
Microsatellite instability and mutation analysis among southern Italian patients with colorectal carcinoma: detection of different alterations accounting for MLH1 and MSH2 inactivation in familial cases.
14504054
2003
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Neoplasms
0.700
GeneticVariation
CLINVAR
The interaction of the human MutL homologues in hereditary nonpolyposis colon cancer.
10037723
1999
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Neoplasms
0.700
CausalMutation
CLINVAR
Ten novel MSH2 and MLH1 germline mutations in families with HNPCC.
15365996
2004
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Neoplasms
0.700
CausalMutation
CLINVAR
Germline MLH1 and MSH2 mutational spectrum including frequent large genomic aberrations in Hungarian hereditary non-polyposis colorectal cancer families: implications for genetic testing.
17569143
2007
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Neoplasms
0.700
CausalMutation
CLINVAR
A survey of the clinicopathological and molecular characteristics of patients with suspected Lynch syndrome in Latin America.
28874130
2017
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Neoplasms
0.700
CausalMutation
CLINVAR
Functional implications of the p.Cys680Arg mutation in the MLH1 mismatch repair protein.
25077178
2014
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Neoplasms
0.700
CausalMutation
CLINVAR
Verification of the three-step model in assessing the pathogenicity of mismatch repair gene variants.
21120944
2011
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Neoplasms
0.700
CausalMutation
CLINVAR
Breast carcinoma and Lynch syndrome: molecular analysis of tumors arising in mutation carriers, non-carriers, and sporadic cases.
22691310
2012
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Neoplasms
0.700
GeneticVariation
CLINVAR
Impact of genetic counseling and DNA testing on individuals with colorectal cancer with a positive family history: a population-based study.
16379545
2005
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Neoplasms
0.700
CausalMutation
CLINVAR
A mononucleotide markers panel to identify hMLH1/hMSH2 germline mutations.
17473388
2007
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Neoplasms
0.700
CausalMutation
CLINVAR
Integrated analysis of unclassified variants in mismatch repair genes.
21239990
2011
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Neoplasms
0.700
GeneticVariation
CLINVAR
Conventional and tissue microarray immunohistochemical expression analysis of mismatch repair in hereditary colorectal tumors.
12547705
2003