×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of stomach
0.400
Biomarker
BEFREE
CD44 is a potential target of amplification within the 11p13 amplicon detected in gastric cancer cell lines.11066075 2000
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of stomach
0.400
Biomarker
BEFREE
CD44 is a transmembrane receptor for hyaluronan and osteopontin, and has recently attracted attention as a gastric cancer stem cell marker.21105049 2011
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of stomach
0.400
GeneticVariation
BEFREE
CD44 -SLC1A2 gene fusions in gastric cancer .21471434 2011
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of stomach
0.400
Biomarker
BEFREE
CD44 is a cell surface protein and it is widely used as a cancer stem cell marker in various cancer types including gastric cancer .25081334 2014
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of stomach
0.400
GeneticVariation
BEFREE
CD44 single nucleotide polymorphism and isoform switching may predict gastric cancer recurrence.26416034 2015
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of stomach
0.400
Biomarker
BEFREE
CD44 -positive cancer stem-like cells at the invasive tumour front indicate poor survival and can be a unique biological prognostic factor for GC .27931044 2017
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of stomach
0.400
Biomarker
BEFREE
A CD44 specific peptide developed by phage display for targeting gastric cancer .
26140900 2015
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of stomach
0.400
Biomarker
BEFREE
Aberrant expression and amplification of the c-met gene, inactivation of the p53 gene, and CD44 abnormal transcripts are common events of both well differentiated and poorly differentiated gastric cancers .
7676688 1995
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of stomach
0.400
GeneticVariation
BEFREE
Besides, CD44 variant isoform 6 (CD44v6), a protein marker for metastatic behavior in gastric cancer , and was chose as the target gene to further analyze the siRNA delivery function of PEG-g-PEI-SPION.
23179610 2013
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of stomach
0.400
Biomarker
BEFREE
Cancer stem cell (CSC) with the mark of CD44 played an important role in GC . rMETase was wildly exploited as chemotherapeutic option for GC .
29858680 2018
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of stomach
0.400
GeneticVariation
BEFREE
CD44E is a frequently overexpressed variant of CD44 in gastric cancer .
26119931 2016
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of stomach
0.400
AlteredExpression
BEFREE
Chimeric 5/35 adenovirus-mediated Dickkopf-1 overexpression suppressed tumorigenicity of CD44 ⁺ gastric cancer cells via attenuating Wnt signaling.
23188090 2013
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of stomach
0.400
Biomarker
BEFREE
Circulating tumor cells expressing cancer stem cell marker CD44 as a diagnostic biomarker in patients with gastric cancer .
28123556 2017
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of stomach
0.400
AlteredExpression
BEFREE
De-novo expression of CD44 and survival in gastric cancer .
7692200 1993
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of stomach
0.400
Biomarker
BEFREE
Despite their suggested importance, the mechanistic roles of FGFR2 and gastric cancer stem cell (GCSC) marker CD44 remain unclear.
27107424 2016
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of stomach
0.400
GeneticVariation
BEFREE
Expression and prognostic value of the CD44 splicing variants v5 and v6 in gastric cancer .
9390037 1997
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of stomach
0.400
GeneticVariation
BEFREE
Expression of CD44 variant exons 8-10 in gastric cancer .
8636005 1995
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of stomach
0.400
AlteredExpression
BEFREE
Expression of hyaluronan receptors CD44 and RHAMM in stomach cancers : relevance with tumor progression.
11029494 2000
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of stomach
0.400
GeneticVariation
BEFREE
Haplotypes of OPN and CD44 variants significantly influenced risk of gastric cancer .
25009318 2014
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of stomach
0.400
Biomarker
BEFREE
HOXA10(+)/CD44 (+) expression might serve as a prognostic biomarker for GC , which needs more studies to validate.
26552644 2015
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of stomach
0.400
AlteredExpression
BEFREE
Immunohistochemistry, immunofluorescence, and Fluorescence activated cell sorting (FACS) were used to determine CD44 and Hairy enhancer of split-1 (Hes1) expression in human GC tissues.
28186678 2017
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of stomach
0.400
AlteredExpression
BEFREE
In a series of gastric cancer specimens, we found strong correlations among Wnt1 expression, CD44 expression, and the grade of gastric cancer .
24481453 2014
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of stomach
0.400
AlteredExpression
BEFREE
In addition, expression of CD44 variants containing exons V5 and V6 may be used as an indicator of evolving gastric cancer .
7531611 1995
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of stomach
0.400
Biomarker
BEFREE
In conclusion, results of the present study indicated that HDAC1 depletion inhibits the metastatic abilities of gastric cancer cells by regulating the miRNA-34a/CD44 pathway, which may be a potential target for the treatment of gastric cancer .
26035691 2015
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of stomach
0.400
AlteredExpression
BEFREE
In general, genetic instability, telomerase activity, CD44 abnormal transcripts, and p53 mutation, all of which are common events of two types of gastric cancer , may be involved mainly in the early stage of stomach carcinogenesis, whereas activation of oncogenes and overexpression of the epidermal growth factor-related growth factor system may chiefly confer progression on gastric cancer .
8658214 1996