×
Entrez Id:
3553
Gene Symbol:
IL1B
IL1B
Chemical and Drug Induced Liver Injury
0.500
Biomarker
CTD_human
Acetaminophen-induced hepatotoxicity in mice is dependent on Tlr9 and the Nalp3 inflammasome.
19164858
2009
×
Entrez Id:
7124
Gene Symbol:
TNF
TNF
Chemical and Drug Induced Liver Injury
0.500
Biomarker
CTD_human
Phenotypic and genotypic assessment of concomitant drug-induced toxic effects in liver, kidney and blood.
20623750
2011
×
Entrez Id:
7124
Gene Symbol:
TNF
TNF
Chemical and Drug Induced Liver Injury
0.500
Therapeutic
CTD_human
Trovafloxacin enhances TNF-induced inflammatory stress and cell death signaling and reduces TNF clearance in a murine model of idiosyncratic hepatotoxicity.
19638433
2009
×
Entrez Id:
2729
Gene Symbol:
GCLC
GCLC
Chemical and Drug Induced Liver Injury
0.500
Biomarker
CTD_human
Drug-induced hepatotoxicity test using gamma-glutamylcysteine synthetase knockdown rat.
19481141
2009
×
Entrez Id:
7124
Gene Symbol:
TNF
TNF
Chemical and Drug Induced Liver Injury
0.500
Therapeutic
CTD_human
Lipopolysaccharide and trovafloxacin coexposure in mice causes idiosyncrasy-like liver injury dependent on tumor necrosis factor-alpha.
17709330
2007
×
Entrez Id:
3162
Gene Symbol:
HMOX1
HMOX1
Chemical and Drug Induced Liver Injury
0.500
Therapeutic
CTD_human
Urinary excretion of bilirubin oxidative metabolites in arsenite-treated mice.
22688006
2012
×
Entrez Id:
5428
Gene Symbol:
POLG
POLG
Chemical and Drug Induced Liver Injury
0.500
Biomarker
CTD_human
POLG DNA testing as an emerging standard of care before instituting valproic acid therapy for pediatric seizure disorders.
20138553
2010
×
Entrez Id:
847
Gene Symbol:
CAT
CAT
Chemical and Drug Induced Liver Injury
0.500
Biomarker
CTD_human
Phenotypic and genotypic assessment of concomitant drug-induced toxic effects in liver, kidney and blood.
20623750
2011
×
Entrez Id:
7124
Gene Symbol:
TNF
TNF
Chemical and Drug Induced Liver Injury
0.500
Therapeutic
CTD_human
Amiodarone exposure during modest inflammation induces idiosyncrasy-like liver injury in rats: role of tumor necrosis factor-alpha.
21984482
2012
×
Entrez Id:
3553
Gene Symbol:
IL1B
IL1B
Chemical and Drug Induced Liver Injury
0.500
Therapeutic
CTD_human
Prediction of drug-induced liver injury using keratinocytes.
28138970
2017
×
Entrez Id:
3553
Gene Symbol:
IL1B
IL1B
Chemical and Drug Induced Liver Injury
0.500
Biomarker
CTD_human
Prediction of drug-induced liver injury using keratinocytes.
28138970
2017
×
Entrez Id:
7450
Gene Symbol:
VWF
VWF
Chemical and Drug Induced Liver Injury
0.500
Biomarker
CTD_human
Von Willebrand factor deficiency reduces liver fibrosis in mice.
28527913
2017
×
Entrez Id:
2875
Gene Symbol:
GPT
GPT
Chemical and Drug Induced Liver Injury
0.500
Biomarker
CTD_human
Determination of the key innate genes related to individual variation in carbon tetrachloride-induced hepatotoxicity using a pre-biopsy procedure.
19481104
2009
×
Entrez Id:
60
Gene Symbol:
ACTB
ACTB
Chemical and Drug Induced Liver Injury
0.500
Biomarker
CTD_human
Characteristic molecular and proteomic signatures of drug-induced liver injury in a rat model.
25231249
2015
×
Entrez Id:
7124
Gene Symbol:
TNF
TNF
Chemical and Drug Induced Liver Injury
0.500
Biomarker
CTD_human
Trovafloxacin enhances TNF-induced inflammatory stress and cell death signaling and reduces TNF clearance in a murine model of idiosyncratic hepatotoxicity.
19638433
2009
×
Entrez Id:
2944
Gene Symbol:
GSTM1
GSTM1
Chemical and Drug Induced Liver Injury
0.500
Biomarker
CTD_human
Glutathione S-transferase m1 and t1 null genotypes increase susceptibility to idiosyncratic drug-induced liver injury.
18666253
2008
×
Entrez Id:
3162
Gene Symbol:
HMOX1
HMOX1
Chemical and Drug Induced Liver Injury
0.500
Biomarker
CTD_human
Urinary excretion of bilirubin oxidative metabolites in arsenite-treated mice.
22688006
2012
×
Entrez Id:
2936
Gene Symbol:
GSR
GSR
Chemical and Drug Induced Liver Injury
0.500
Biomarker
CTD_human
Editor's Highlight: Transgenic Zebrafish Reporter Lines as Alternative In Vivo Organ Toxicity Models.
28069987
2017
×
Entrez Id:
3162
Gene Symbol:
HMOX1
HMOX1
Chemical and Drug Induced Liver Injury
0.500
Biomarker
CTD_human
Markers of electrophilic stress caused by chemically reactive metabolites in human hepatocytes.
18227147
2008
×
Entrez Id:
5243
Gene Symbol:
ABCB1
ABCB1
Chemical and Drug Induced Liver Injury
0.500
Biomarker
CTD_human
Phenotypic and genotypic assessment of concomitant drug-induced toxic effects in liver, kidney and blood.
20623750
2011
×
Entrez Id:
1571
Gene Symbol:
CYP2E1
CYP2E1
Chemical and Drug Induced Liver Injury
0.500
Biomarker
CTD_human
CYP2E1 genotype and isoniazid-induced hepatotoxicity in patients treated for latent tuberculosis.
16770646
2006
×
Entrez Id:
761
Gene Symbol:
CA3
CA3
Chemical and Drug Induced Liver Injury
0.500
Biomarker
CTD_human
Characteristic molecular and proteomic signatures of drug-induced liver injury in a rat model.
25231249
2015
×
Entrez Id:
7124
Gene Symbol:
TNF
TNF
Chemical and Drug Induced Liver Injury
0.500
Biomarker
CTD_human
Amiodarone exposure during modest inflammation induces idiosyncrasy-like liver injury in rats: role of tumor necrosis factor-alpha.
21984482
2012
×
Entrez Id:
5428
Gene Symbol:
POLG
POLG
Chemical and Drug Induced Liver Injury
0.500
Biomarker
CTD_human
Reversible valproate hepatotoxicity due to mutations in mitochondrial DNA polymerase gamma (POLG1).
18208989
2008
×
Entrez Id:
7124
Gene Symbol:
TNF
TNF
Chemical and Drug Induced Liver Injury
0.500
Biomarker
CTD_human
Lipopolysaccharide and trovafloxacin coexposure in mice causes idiosyncrasy-like liver injury dependent on tumor necrosis factor-alpha.
17709330
2007