Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 10157
Gene Symbol: AASS
AASS
Chemical and Drug Induced Liver Injury
0.300 Biomarker CTD_human Characteristic molecular and proteomic signatures of drug-induced liver injury in a rat model. 25231249

2015

Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
Chemical and Drug Induced Liver Injury
0.500 Biomarker CTD_human Phenotypic and genotypic assessment of concomitant drug-induced toxic effects in liver, kidney and blood. 20623750

2011

Entrez Id: 4363
Gene Symbol: ABCC1
ABCC1
Chemical and Drug Induced Liver Injury
0.300 Biomarker CTD_human Defining targets for investigating the pharmacogenomics of adverse drug reactions to antifungal agents. 18466103

2008

Entrez Id: 1244
Gene Symbol: ABCC2
ABCC2
Chemical and Drug Induced Liver Injury
0.300 Biomarker CTD_human Defining targets for investigating the pharmacogenomics of adverse drug reactions to antifungal agents. 18466103

2008

Entrez Id: 1244
Gene Symbol: ABCC2
ABCC2
Chemical and Drug Induced Liver Injury
0.300 Biomarker CTD_human Methotrexate (MTX) pathway gene polymorphisms and their effects on MTX toxicity in Caucasian and African American patients with rheumatoid arthritis. 18381794

2008

Entrez Id: 10006
Gene Symbol: ABI1
ABI1
Chemical and Drug Induced Liver Injury
0.300 Biomarker CTD_human Characteristic molecular and proteomic signatures of drug-induced liver injury in a rat model. 25231249

2015

Entrez Id: 8310
Gene Symbol: ACOX3
ACOX3
Chemical and Drug Induced Liver Injury
0.300 Biomarker CTD_human Characteristic molecular and proteomic signatures of drug-induced liver injury in a rat model. 25231249

2015

Entrez Id: 2180
Gene Symbol: ACSL1
ACSL1
Chemical and Drug Induced Liver Injury
0.300 Biomarker CTD_human Characteristic molecular and proteomic signatures of drug-induced liver injury in a rat model. 25231249

2015

Entrez Id: 60
Gene Symbol: ACTB
ACTB
Chemical and Drug Induced Liver Injury
0.500 Biomarker CTD_human Characteristic molecular and proteomic signatures of drug-induced liver injury in a rat model. 25231249

2015

Entrez Id: 81
Gene Symbol: ACTN4
ACTN4
Chemical and Drug Induced Liver Injury
0.300 Biomarker CTD_human Characteristic molecular and proteomic signatures of drug-induced liver injury in a rat model. 25231249

2015

Entrez Id: 10096
Gene Symbol: ACTR3
ACTR3
Chemical and Drug Induced Liver Injury
0.300 Biomarker CTD_human Characteristic molecular and proteomic signatures of drug-induced liver injury in a rat model. 25231249

2015

Entrez Id: 101
Gene Symbol: ADAM8
ADAM8
Chemical and Drug Induced Liver Injury
0.300 Biomarker CTD_human Neutralization of ADAM8 ameliorates liver injury and accelerates liver repair in carbon tetrachloride-induced acute liver injury. 24646716

2014

Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
Chemical and Drug Induced Liver Injury
0.300 Therapeutic CTD_human Adiponectin-mediated heme oxygenase-1 induction protects against iron-induced liver injury via a PPARα dependent mechanism. 20709802

2010

Entrez Id: 183
Gene Symbol: AGT
AGT
Chemical and Drug Induced Liver Injury
0.300 Biomarker CTD_human Metformin treatment prevents SREBP2-mediated cholesterol uptake and improves lipid homeostasis during oxidative stress-induced atherosclerosis. 29499335

2018

Entrez Id: 196
Gene Symbol: AHR
AHR
Chemical and Drug Induced Liver Injury
0.300 Biomarker CTD_human Aryl hydrocarbon receptor-mediated induction of Stearoyl-CoA desaturase 1 alters hepatic fatty acid composition in TCDD-elicited steatosis. 21890736

2011

Entrez Id: 9131
Gene Symbol: AIFM1
AIFM1
Chemical and Drug Induced Liver Injury
0.300 Biomarker CTD_human Hepatitis C virus structural proteins can exacerbate or ameliorate acetaminophen-induced liver injury in mice. 25743375

2015

Entrez Id: 213
Gene Symbol: ALB
ALB
Chemical and Drug Induced Liver Injury
0.300 Biomarker CTD_human Mangiferin exerts hepatoprotective activity against D-galactosamine induced acute toxicity and oxidative/nitrosative stress via Nrf2-NFκB pathways. 22310181

2012

Entrez Id: 213
Gene Symbol: ALB
ALB
Chemical and Drug Induced Liver Injury
0.300 Biomarker CTD_human Detection of cell-free, liver-specific mRNAs in peripheral blood from rats with hepatotoxicity: a potential toxicological biomarker for safety evaluation. 18779383

2008

Entrez Id: 160428
Gene Symbol: ALDH1L2
ALDH1L2
Chemical and Drug Induced Liver Injury
0.300 Biomarker CTD_human Characteristic molecular and proteomic signatures of drug-induced liver injury in a rat model. 25231249

2015

Entrez Id: 223
Gene Symbol: ALDH9A1
ALDH9A1
Chemical and Drug Induced Liver Injury
0.300 Biomarker CTD_human Characteristic molecular and proteomic signatures of drug-induced liver injury in a rat model. 25231249

2015

Entrez Id: 229
Gene Symbol: ALDOB
ALDOB
Chemical and Drug Induced Liver Injury
0.300 Biomarker CTD_human Detection of autoantibody to aldolase B in sera from patients with troglitazone-induced liver dysfunction. 16115720

2005

Entrez Id: 259
Gene Symbol: AMBP
AMBP
Chemical and Drug Induced Liver Injury
0.300 Biomarker CTD_human Detection of cell-free, liver-specific mRNAs in peripheral blood from rats with hepatotoxicity: a potential toxicological biomarker for safety evaluation. 18779383

2008

Entrez Id: 302
Gene Symbol: ANXA2
ANXA2
Chemical and Drug Induced Liver Injury
0.300 Biomarker CTD_human Characterization of chemically induced liver injuries using gene co-expression modules. 25226513

2014

Entrez Id: 309
Gene Symbol: ANXA6
ANXA6
Chemical and Drug Induced Liver Injury
0.300 Biomarker CTD_human Characteristic molecular and proteomic signatures of drug-induced liver injury in a rat model. 25231249

2015

Entrez Id: 335
Gene Symbol: APOA1
APOA1
Chemical and Drug Induced Liver Injury
0.300 Biomarker CTD_human Use of proteomic methods to identify serum biomarkers associated with rat liver toxicity or hypertrophy. 16099942

2005