Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
0.360 Therapeutic CTD_human Role of Nrf2 in preventing ethanol-induced oxidative stress and lipid accumulation. 22627062

2012

Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
0.360 Therapeutic CTD_human Nrf2 protects against furosemide-induced hepatotoxicity. 24813929

2014

Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
0.360 Therapeutic CTD_human P450 3A-Catalyzed O-Dealkylation of Lapatinib Induces Mitochondrial Stress and Activates Nrf2. 26958860

2016

Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
0.360 Therapeutic CTD_human Liver-specific loss of Atg5 causes persistent activation of Nrf2 and protects against acetaminophen-induced liver injury. 22491424

2012

Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
0.360 Therapeutic CTD_human Nrf2 Activation Ameliorates Hepatotoxicity Induced by a Heme Synthesis Inhibitor. 30215777

2019