×
Entrez Id: 3423
Gene Symbol: IDS
IDS
Mucopolysaccharidosis II
1.000
GeneticVariation
UNIPROT
Mutation R468W of the iduronate-2-sulfatase gene in mild Hunter syndrome (mucopolysaccharidosis type II) confirmed by in vitro mutagenesis and expression.
1284597 1992
×
Entrez Id: 3423
Gene Symbol: IDS
IDS
Mucopolysaccharidosis II
1.000
GeneticVariation
UNIPROT
Mutation analysis of the iduronate-2-sulfatase gene in patients with mucopolysaccharidosis type II (Hunter syndrome ).
1303211 1992
×
Entrez Id: 3423
Gene Symbol: IDS
IDS
Mucopolysaccharidosis II
1.000
GeneticVariation
UNIPROT
Mucopolysaccharidosis type II (Hunter disease ): identification and characterization of eight point mutations in the iduronate-2-sulfatase gene in Japanese patients.
7581397 1995
×
Entrez Id: 3423
Gene Symbol: IDS
IDS
Mucopolysaccharidosis II
1.000
GeneticVariation
UNIPROT
Mutations of the iduronate-2-sulfatase gene on a T146T background in three patients with Hunter syndrome .
7599640 1995
×
Entrez Id: 3423
Gene Symbol: IDS
IDS
Mucopolysaccharidosis II
1.000
GeneticVariation
UNIPROT
Mutations of the iduronate-2-sulfatase gene in 12 Polish patients with mucopolysaccharidosis type II (Hunter syndrome ).
7728156 1995
×
Entrez Id: 3423
Gene Symbol: IDS
IDS
Mucopolysaccharidosis II
1.000
GeneticVariation
UNIPROT
Mutation analysis of Jewish Hunter patients in Israel.
7866405 1994
×
Entrez Id: 3423
Gene Symbol: IDS
IDS
Mucopolysaccharidosis II
1.000
GeneticVariation
UNIPROT
Molecular diagnosis of mucopolysaccharidosis type II (Hunter syndrome ) by automated sequencing and computer-assisted interpretation: toward mutation mapping of the iduronate-2-sulfatase gene.
7887413 1995
×
Entrez Id: 3423
Gene Symbol: IDS
IDS
Mucopolysaccharidosis II
1.000
GeneticVariation
UNIPROT
Mutations of the iduronate-2-sulfatase (IDS ) gene in patients with Hunter syndrome (mucopolysaccharidosis II ).
7981716 1994
×
Entrez Id: 3423
Gene Symbol: IDS
IDS
Mucopolysaccharidosis II
1.000
GeneticVariation
UNIPROT
Iduronate-2-sulfatase gene mutations in 16 patients with mucopolysaccharidosis type II (Hunter syndrome ).8281149 1993
×
Entrez Id: 3423
Gene Symbol: IDS
IDS
Mucopolysaccharidosis II
1.000
GeneticVariation
UNIPROT
Mutations in the iduronate-2-sulfatase gene in five Norwegians with Hunter syndrome .
8566953 1996
×
Entrez Id: 3423
Gene Symbol: IDS
IDS
Mucopolysaccharidosis II
1.000
GeneticVariation
UNIPROT
Mutation analysis in 20 patients with Hunter disease.
8664909 1996
×
Entrez Id: 3423
Gene Symbol: IDS
IDS
Mucopolysaccharidosis II
1.000
GeneticVariation
UNIPROT
Detection of four novel mutations in the iduronate-2-sulphatase gene by single-strand conformation polymorphism analysis of genomic amplicons.
8830188 1996
×
Entrez Id: 3423
Gene Symbol: IDS
IDS
Mucopolysaccharidosis II
1.000
GeneticVariation
UNIPROT
Mucopolysaccharidosis type II (Hunter syndrome ): mutation "hot spots" in the iduronate-2-sulfatase gene.
8940265 1996
×
Entrez Id: 3423
Gene Symbol: IDS
IDS
Mucopolysaccharidosis II
1.000
GeneticVariation
UNIPROT
Mucopolysaccharidosis type II: identification of six novel mutations in Italian patients.
9222763 1997
×
Entrez Id: 3423
Gene Symbol: IDS
IDS
Mucopolysaccharidosis II
1.000
GeneticVariation
UNIPROT
Molecular analysis in 23 Hunter disease families.
9266380 1997
×
Entrez Id: 3423
Gene Symbol: IDS
IDS
Mucopolysaccharidosis II
1.000
GeneticVariation
UNIPROT
In a sequence analysis of the iduronate-2-sulfatase gene, evidence was obtained for the R468Q (G1403 to A) mutation, a common one in Hunter disease .
9375851 1997
×
Entrez Id: 3423
Gene Symbol: IDS
IDS
Mucopolysaccharidosis II
1.000
GeneticVariation
UNIPROT
Mutations in the iduronate-2-sulfatase gene in 12 Spanish patients with Hunter disease .
9452044 1998
×
Entrez Id: 3423
Gene Symbol: IDS
IDS
Mucopolysaccharidosis II
1.000
GeneticVariation
UNIPROT
Our series of studies on Hunter disease in Japanese patients showed allelic heterogeneity of IDS gene mutations, genotype/phenotype correlation and racial differences in distribution of mutations.
9501270 1998
×
Entrez Id: 3423
Gene Symbol: IDS
IDS
Mucopolysaccharidosis II
1.000
GeneticVariation
UNIPROT
Identification of iduronate sulfatase gene alterations in 70 unrelated Hunter patients.
9660053 1998
×
Entrez Id: 3423
Gene Symbol: IDS
IDS
Mucopolysaccharidosis II
1.000
GeneticVariation
UNIPROT
Hunter disease in the Spanish population: molecular analysis in 31 families.
9762601 1998
×
Entrez Id: 3423
Gene Symbol: IDS
IDS
Mucopolysaccharidosis II
1.000
GeneticVariation
UNIPROT
Mutation analysis in 57 unrelated patients with MPS II (Hunter's disease ).
9875019 1998
×
Entrez Id: 3423
Gene Symbol: IDS
IDS
Mucopolysaccharidosis II
1.000
GeneticVariation
UNIPROT
Mutational spectrum of the iduronate-2-sulfatase (IDS ) gene in 36 unrelated Russian MPS II patients.
9921913 1998
×
Entrez Id: 3423
Gene Symbol: IDS
IDS
Mucopolysaccharidosis II
1.000
GeneticVariation
UNIPROT
Mucopolysaccharidosis type II (Hunter syndrome ) is an X linked lysosomal storage disorder resulting from heterogeneous mutations in the iduronate-2-sulphatase (IDS ) gene.
9950361 1999
×
Entrez Id: 3423
Gene Symbol: IDS
IDS
Mucopolysaccharidosis II
1.000
GeneticVariation
UNIPROT
Hunter disease (mucopolysaccharidosis type II or MPS II ) is an X-linked recessive disorder caused by the deficiency of the lysosomal enzyme iduronate-2-sulfatase (IDS ) (E.C.3.1.6.13.) involved in the catabolism of mucopolysaccharides dermatan sulfate and heparan sulfate.10215411 1998
×
Entrez Id: 3423
Gene Symbol: IDS
IDS
Mucopolysaccharidosis II
1.000
GeneticVariation
UNIPROT
We sequenced genomic DNA and RT-PCR products in the iduronate sulfatase (IDS ) gene in 6 unrelated patients with Hunter syndrome to assess genotype/phenotype relationships and offer carrier testing where required.
10220152 1999