Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.400 Biomarker BEFREE Gastric cancer in young vs old Romanian patients: immunoprofile with emphasis on maspin and mena protein reactivity. 25556597

2015

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.400 Biomarker BEFREE Epidermal growth factor receptor and c-erbB-2 contents in unresectable (UICC R1 or R2) gastric cancer. 14535591

2004

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.400 AlteredExpression BEFREE Epidermal growth factor receptor (EGFR): mutational and protein expression analysis in gastric cancer. 17094480

2006

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.400 GeneticVariation BEFREE Epidermal growth factor receptor mutation in gastric cancer. 21436633

2011

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.400 GeneticVariation BEFREE Epidermal growth factor receptor gene polymorphisms and gastric cancer in Iran. 23803102

2013

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.400 Biomarker BEFREE EGFR GCN gain is a more accurate prognostic biomarker than EGFR overexpression in patients with gastric cancer. 25487305

2016

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.400 GeneticVariation BEFREE EGFR gene polymorphisms -216G>T and -191C>A are risk markers for gastric cancer in Mexican population. 25867325

2015

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.400 Biomarker BEFREE EGFR and HER2 signals play a salvage role in MEK1-mutated gastric cancer after MEK inhibition. 26081723

2015

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.400 Biomarker BEFREE Epidermal growth factor receptor positivity was an independent favorable prognostic factor for gastric cancer, especially in Stage III disease. 27008850

2016

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.400 Biomarker BEFREE Epidermal growth factor receptor (EGFR) plays an important role in gastric cancer (GC) progression. 29150923

2018

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.400 Biomarker BEFREE ErbB1 and ErbB3 expressions were analyzed by immunohistochemistry and real-time PCR in 50 patients with gastric cancer. 30621788

2019

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.400 AlteredExpression BEFREE EGFR overexpression in gastric cancer (GC) has been reported in about 30% of patients. 30815759

2019

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.400 Biomarker BEFREE Epidermal Growth Factor Receptor Family and its Role in Gastric Cancer. 31850207

2019

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.400 Biomarker BEFREE A cross-talk between integrin β4 and epidermal growth factor receptor induces gefitinib chemoresistance to gastric cancer. 29618949

2018

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.400 AlteredExpression BEFREE Accurate measurement of Human epidermal growth factor receptor (HER2) gene expression is central for breast or stomach cancer therapy orientation and prognosis. 28039034

2017

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.400 Biomarker BEFREE Amplification of epidermal growth factor receptor gene and its relationship to survival in human gastric cancer. 7715901

1995

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.400 GeneticVariation BEFREE An epidermal growth factor receptor mutation in exon 19 was identified in mucin-producing gastric cancer sample from a male patient. 27004903

2016

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.400 AlteredExpression BEFREE Because of the causal involvement of EGFR and its ligands in gastric cancer growth, we investigated expression of ERRP and cell proliferation in human gastric cancer. 15647181

2005

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.400 Biomarker BEFREE Blocking EGFR/ATXN2L signaling reversed GC cell oxaliplatin resistance and inhibited migration. 30787271

2019

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.400 Biomarker BEFREE By targeting AR and EGFR using a potent AR inhibitor such as Enzalutamide, we postulate the possible crosstalk between EGFR and AR pathways in GC. 31566139

2019

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.400 AlteredExpression BEFREE Cetuximab is effective in K-ras wild-type, EGFR-expressing gastric cancer cell lines and xenografts. 22011788

2012

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.400 Biomarker BEFREE Cetuximab, an immunoglobulin G1 chimeric monoclonal antibody directed against the epidermal growth factor receptor, is currently considered to be the strategy with the most potential for the treatment of gastric cancer due to the low frequency of KRAS mutations in patients with gastric cancer. 25815786

2015

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.400 Biomarker BEFREE Coactivation of HER1 with cMET renders GCs with a shorter disease-free survival as compared to only cMET activated GCs. 23372746

2013

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.400 Biomarker BEFREE Combination treatment regimens with EGFR-targeting agents and cytotoxic agents are considered to be a potential therapeutic option for EGFR-overexpressing GC. 22139134

2012

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.400 Biomarker BEFREE Cooperative expression of the amplified c-myc and c-erbB-1 genes might be involved in the genesis or progression of the gastric cancer. 3102422

1986