Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 960
Gene Symbol: CD44
CD44
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.400 Biomarker BEFREE In conclusion, results of the present study indicated that HDAC1 depletion inhibits the metastatic abilities of gastric cancer cells by regulating the miRNA-34a/CD44 pathway, which may be a potential target for the treatment of gastric cancer. 26035691

2015

Entrez Id: 960
Gene Symbol: CD44
CD44
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.400 Biomarker BEFREE A CD44 specific peptide developed by phage display for targeting gastric cancer. 26140900

2015

Entrez Id: 960
Gene Symbol: CD44
CD44
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.400 Biomarker BEFREE We recently identified miR-328 as one of the microRNAs targeting CD44 in gastric cancer. 25479940

2015

Entrez Id: 960
Gene Symbol: CD44
CD44
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.400 Biomarker BEFREE HOXA10(+)/CD44(+) expression might serve as a prognostic biomarker for GC, which needs more studies to validate. 26552644

2015

Entrez Id: 960
Gene Symbol: CD44
CD44
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.400 GeneticVariation BEFREE CD44 single nucleotide polymorphism and isoform switching may predict gastric cancer recurrence. 26416034

2015

Entrez Id: 960
Gene Symbol: CD44
CD44
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.400 Biomarker BEFREE Long noncoding RNA GAPLINC regulates CD44-dependent cell invasiveness and associates with poor prognosis of gastric cancer. 25277524

2014

Entrez Id: 960
Gene Symbol: CD44
CD44
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.400 GeneticVariation BEFREE Haplotypes of OPN and CD44 variants significantly influenced risk of gastric cancer. 25009318

2014

Entrez Id: 960
Gene Symbol: CD44
CD44
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.400 AlteredExpression BEFREE This study aimed to explore changes in CD44 and CD24 expression levels in patients with gastric cancer and to assess their prognostic values. 25212506

2014

Entrez Id: 960
Gene Symbol: CD44
CD44
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.400 Biomarker BEFREE CD44 is a cell surface protein and it is widely used as a cancer stem cell marker in various cancer types including gastric cancer. 25081334

2014

Entrez Id: 960
Gene Symbol: CD44
CD44
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.400 AlteredExpression BEFREE In a series of gastric cancer specimens, we found strong correlations among Wnt1 expression, CD44 expression, and the grade of gastric cancer. 24481453

2014

Entrez Id: 960
Gene Symbol: CD44
CD44
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.400 GeneticVariation BEFREE Besides, CD44 variant isoform 6 (CD44v6), a protein marker for metastatic behavior in gastric cancer, and was chose as the target gene to further analyze the siRNA delivery function of PEG-g-PEI-SPION. 23179610

2013

Entrez Id: 960
Gene Symbol: CD44
CD44
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.400 Biomarker BEFREE The CD44+ gastric cancer cell model is a non-adhesion, 3-dimensional, spheroid phenotype. 23900519

2013

Entrez Id: 960
Gene Symbol: CD44
CD44
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.400 AlteredExpression BEFREE Chimeric 5/35 adenovirus-mediated Dickkopf-1 overexpression suppressed tumorigenicity of CD44gastric cancer cells via attenuating Wnt signaling. 23188090

2013

Entrez Id: 960
Gene Symbol: CD44
CD44
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.400 Biomarker BEFREE In the present study, we identified three frequently amplified genes from 30 candidate genes using real-time quantitative PCR method, including ERBB4, C-MET and CD44, and further explored their association with clinicopathological characteristics and poor survival in a cohort of gastric cancers. 22606006

2012

Entrez Id: 960
Gene Symbol: CD44
CD44
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.400 Biomarker BEFREE Recently, the CD44 molecule was reported to be a marker of cancer stem cells in gastric cancer. 21331451

2011

Entrez Id: 960
Gene Symbol: CD44
CD44
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.400 GeneticVariation BEFREE CD44-SLC1A2 gene fusions in gastric cancer. 21471434

2011

Entrez Id: 960
Gene Symbol: CD44
CD44
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.400 Biomarker BEFREE CD44 is a transmembrane receptor for hyaluronan and osteopontin, and has recently attracted attention as a gastric cancer stem cell marker. 21105049

2011

Entrez Id: 960
Gene Symbol: CD44
CD44
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.400 GeneticVariation BEFREE We established the pattern of CD44 variant forms in normal stomach and gastric malignancy. 20856229

2010

Entrez Id: 960
Gene Symbol: CD44
CD44
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.400 AlteredExpression BEFREE To detect the expression of CD44 correlated with the ability of micro-metastasis in peripheral blood and bone marrow of patients with gastric cancer and to deduce its clinical significance. 16440414

2006

Entrez Id: 960
Gene Symbol: CD44
CD44
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.400 AlteredExpression BEFREE So far, the combined status of beta-catenin and TCF4 and its relevance for lymph node metastasis and CD44 expression have not been well studied in gastric cancers (GCs). 16311123

2005

Entrez Id: 960
Gene Symbol: CD44
CD44
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.400 Biomarker BEFREE CD44 is a potential target of amplification within the 11p13 amplicon detected in gastric cancer cell lines. 11066075

2000

Entrez Id: 960
Gene Symbol: CD44
CD44
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.400 AlteredExpression BEFREE Expression of hyaluronan receptors CD44 and RHAMM in stomach cancers: relevance with tumor progression. 11029494

2000

Entrez Id: 960
Gene Symbol: CD44
CD44
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.400 AlteredExpression BEFREE Multivariate analysis demonstrated that CD44 expression and lymph node metastasis in gastric cancer and CD44 and sialyl Lea expression in colorectal cancer were significantly related to hepatic metastasis. 9772282

1998

Entrez Id: 960
Gene Symbol: CD44
CD44
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.400 GeneticVariation BEFREE Expression and prognostic value of the CD44 splicing variants v5 and v6 in gastric cancer. 9390037

1997

Entrez Id: 960
Gene Symbol: CD44
CD44
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.400 AlteredExpression BEFREE In general, genetic instability, telomerase activity, CD44 abnormal transcripts, and p53 mutation, all of which are common events of two types of gastric cancer, may be involved mainly in the early stage of stomach carcinogenesis, whereas activation of oncogenes and overexpression of the epidermal growth factor-related growth factor system may chiefly confer progression on gastric cancer. 8658214

1996