Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1548
Gene Symbol: CYP2A6
CYP2A6
Chemical and Drug Induced Liver Injury
0.500 Biomarker CTD_human Effects of CYP inhibitors on precocene I metabolism and toxicity in rat liver slices. 21741958

2011

Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
Chemical and Drug Induced Liver Injury
0.500 Biomarker CTD_human Phenotypic and genotypic assessment of concomitant drug-induced toxic effects in liver, kidney and blood. 20623750

2011

Entrez Id: 1544
Gene Symbol: CYP1A2
CYP1A2
Chemical and Drug Induced Liver Injury
0.300 Biomarker CTD_human Customised in vitro model to detect human metabolism-dependent idiosyncratic drug-induced liver injury. 28762043

2018

Entrez Id: 1571
Gene Symbol: CYP2E1
CYP2E1
Chemical and Drug Induced Liver Injury
0.300 Biomarker CTD_human Customised in vitro model to detect human metabolism-dependent idiosyncratic drug-induced liver injury. 28762043

2018

Entrez Id: 1576
Gene Symbol: CYP3A4
CYP3A4
Chemical and Drug Induced Liver Injury
0.300 Biomarker CTD_human Customised in vitro model to detect human metabolism-dependent idiosyncratic drug-induced liver injury. 28762043

2018

Entrez Id: 3553
Gene Symbol: IL1B
IL1B
Chemical and Drug Induced Liver Injury
0.300 Therapeutic CTD_human Prediction of drug-induced liver injury using keratinocytes. 28138970

2018

Entrez Id: 1559
Gene Symbol: CYP2C9
CYP2C9
Chemical and Drug Induced Liver Injury
0.300 Biomarker CTD_human Customised in vitro model to detect human metabolism-dependent idiosyncratic drug-induced liver injury. 28762043

2018

Entrez Id: 1557
Gene Symbol: CYP2C19
CYP2C19
Chemical and Drug Induced Liver Injury
0.300 Biomarker CTD_human Customised in vitro model to detect human metabolism-dependent idiosyncratic drug-induced liver injury. 28762043

2018

Entrez Id: 8856
Gene Symbol: NR1I2
NR1I2
Chemical and Drug Induced Liver Injury
0.300 Biomarker CTD_human Hepatotoxic effects of cyproconazole and prochloraz in wild-type and hCAR/hPXR mice. 28058446

2018

Entrez Id: 8856
Gene Symbol: NR1I2
NR1I2
Chemical and Drug Induced Liver Injury
0.300 Therapeutic CTD_human Hepatotoxic effects of cyproconazole and prochloraz in wild-type and hCAR/hPXR mice. 28058446

2018

Entrez Id: 1555
Gene Symbol: CYP2B6
CYP2B6
Chemical and Drug Induced Liver Injury
0.300 Biomarker CTD_human Customised in vitro model to detect human metabolism-dependent idiosyncratic drug-induced liver injury. 28762043

2018

Entrez Id: 9970
Gene Symbol: NR1I3
NR1I3
Chemical and Drug Induced Liver Injury
0.300 Therapeutic CTD_human Hepatotoxic effects of cyproconazole and prochloraz in wild-type and hCAR/hPXR mice. 28058446

2018

Entrez Id: 9970
Gene Symbol: NR1I3
NR1I3
Chemical and Drug Induced Liver Injury
0.300 Biomarker CTD_human Hepatotoxic effects of cyproconazole and prochloraz in wild-type and hCAR/hPXR mice. 28058446

2018

Entrez Id: 3553
Gene Symbol: IL1B
IL1B
Chemical and Drug Induced Liver Injury
0.300 Biomarker CTD_human Prediction of drug-induced liver injury using keratinocytes. 28138970

2018

Entrez Id: 406911
Gene Symbol: MIR125B1
MIR125B1
Chemical and Drug Induced Liver Injury
0.300 Biomarker CTD_human Serum microRNA signatures as "liquid biopsies" for interrogating hepatotoxic mechanisms and liver pathogenesis in human. 28545106

2017

Entrez Id: 7450
Gene Symbol: VWF
VWF
Chemical and Drug Induced Liver Injury
0.300 Biomarker CTD_human Von Willebrand factor deficiency reduces liver fibrosis in mice. 28527913

2017

Entrez Id: 407019
Gene Symbol: MIR27B
MIR27B
Chemical and Drug Induced Liver Injury
0.300 Biomarker CTD_human Serum microRNA signatures as "liquid biopsies" for interrogating hepatotoxic mechanisms and liver pathogenesis in human. 28545106

2017

Entrez Id: 7046
Gene Symbol: TGFBR1
TGFBR1
Chemical and Drug Induced Liver Injury
0.300 Biomarker CTD_human Hepatocyte-specific expression of constitutively active Alk5 exacerbates thioacetamide-induced liver injury in mice. 28560358

2017

Entrez Id: 574030
Gene Symbol: MIR362
MIR362
Chemical and Drug Induced Liver Injury
0.300 Biomarker CTD_human Serum microRNA signatures as "liquid biopsies" for interrogating hepatotoxic mechanisms and liver pathogenesis in human. 28545106

2017

Entrez Id: 406920
Gene Symbol: MIR130B
MIR130B
Chemical and Drug Induced Liver Injury
0.300 Biomarker CTD_human Serum microRNA signatures as "liquid biopsies" for interrogating hepatotoxic mechanisms and liver pathogenesis in human. 28545106

2017

Entrez Id: 406967
Gene Symbol: MIR192
MIR192
Chemical and Drug Induced Liver Injury
0.300 Biomarker CTD_human Downregulation of miR-192 causes hepatic steatosis and lipid accumulation by inducing SREBF1: Novel mechanism for bisphenol A-triggered non-alcoholic fatty liver disease. 28483554

2017

Entrez Id: 102466270
Gene Symbol: MIR6741
MIR6741
Chemical and Drug Induced Liver Injury
0.300 Biomarker CTD_human Serum microRNA signatures as "liquid biopsies" for interrogating hepatotoxic mechanisms and liver pathogenesis in human. 28545106

2017

Entrez Id: 102465858
Gene Symbol: MIR7977
MIR7977
Chemical and Drug Induced Liver Injury
0.300 Biomarker CTD_human Serum microRNA signatures as "liquid biopsies" for interrogating hepatotoxic mechanisms and liver pathogenesis in human. 28545106

2017

Entrez Id: 693212
Gene Symbol: MIR627
MIR627
Chemical and Drug Induced Liver Injury
0.300 Biomarker CTD_human Serum microRNA signatures as "liquid biopsies" for interrogating hepatotoxic mechanisms and liver pathogenesis in human. 28545106

2017

Entrez Id: 100616437
Gene Symbol: MIR1343
MIR1343
Chemical and Drug Induced Liver Injury
0.300 Biomarker CTD_human Serum microRNA signatures as "liquid biopsies" for interrogating hepatotoxic mechanisms and liver pathogenesis in human. 28545106

2017