Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 581
Gene Symbol: BAX
BAX
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.520 AlteredExpression BEFREE The expression levels of B cell lymphoma 2 (Bcl‑2) were increased, and the expression levels of caspase‑3, Bcl‑2 associated X protein and AD‑associated proteins were decreased in the hippocampus following treatment with vildagliptin. 29257340

2018
Entrez Id: 581
Gene Symbol: BAX
BAX
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.520 Therapeutic RGD Bajijiasu Ameliorates β-Amyloid-Triggered Endoplasmic Reticulum Stress and Related Pathologies in an Alzheimer's Disease Model. 29587274

2018
Entrez Id: 581
Gene Symbol: BAX
BAX
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.520 Therapeutic RGD CART peptide activates the Nrf2/HO-1 antioxidant pathway and protects hippocampal neurons in a rat model of Alzheimer's disease. 29777699

2018
Entrez Id: 581
Gene Symbol: BAX
BAX
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.520 Therapeutic RGD "Xiusanzhen" can regulate the expression of hippocampal Bcl-2 and Bax proteins in AD rats, which may contribute to its clinical effect in relieving AD, and the therapeutic effect depends on the integrity of the olfactory nerve pathway. 21585051

2011
Entrez Id: 581
Gene Symbol: BAX
BAX
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.520 Biomarker CTD_human Loss of phospholipid asymmetry and elevated brain apoptotic protein levels in subjects with amnestic mild cognitive impairment and Alzheimer disease. 18077176

2008
Entrez Id: 581
Gene Symbol: BAX
BAX
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.520 Biomarker RGD [Effects of TX0201 abstracted from heart-regulating formula on spatial learning and regulation of Bax mRNA, Bcl-2 mRNA level in brain of rat with Alzheimer's disease]. 17639989

2007
Entrez Id: 581
Gene Symbol: BAX
BAX
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.520 Biomarker RGD Induction of Bcl-2 and Bax was related to hyperphosphorylation of tau and neuronal death induced by okadaic acid in rat brain. 16265626

2005
Entrez Id: 581
Gene Symbol: BAX
BAX
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.520 Biomarker BEFREE Consequently, we examined the expression of bcl-associated X (Bax) protein in AD brain. 8990132

1997