Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
CUI: C0015695
Disease: Fatty Liver
Fatty Liver
0.520 Biomarker BEFREE PTEN negatively regulates the enzymes involved in hepatic gluconeogenesis and lipid synthesis, which suggests that PTEN may be a therapeutic target for ketosis and fatty liver in dairy cows. 30819264

2019

Entrez Id: 5728
Gene Symbol: PTEN
PTEN
CUI: C0015695
Disease: Fatty Liver
Fatty Liver
0.520 Biomarker CTD_human Toll-like Receptor 4 on Macrophage Promotes the Development of Steatohepatitis-related Hepatocellular Carcinoma in Mice. 27022031

2016

Entrez Id: 5728
Gene Symbol: PTEN
PTEN
CUI: C0015695
Disease: Fatty Liver
Fatty Liver
0.520 AlteredExpression BEFREE In conclusion, OA activates GPR40-PLC-calcium pathway to increase the expression of PPARδ and PPARδ further decreased the expression of PTEN to regulate insulin sensitivity in hepatic steatosis. 22209682

2012

Entrez Id: 5728
Gene Symbol: PTEN
PTEN
CUI: C0015695
Disease: Fatty Liver
Fatty Liver
0.520 Biomarker RGD PTEN down-regulation by unsaturated fatty acids triggers hepatic steatosis via an NF-kappaBp65/mTOR-dependent mechanism. 18166358

2008

Entrez Id: 5728
Gene Symbol: PTEN
PTEN
CUI: C0015695
Disease: Fatty Liver
Fatty Liver
0.520 Biomarker MGD