Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0029925
Disease: Ovarian Carcinoma
Ovarian Carcinoma
0.470 GeneticVariation BEFREE Additionally, RAS/RAF/MEK/ERK pathway-targeted therapy may benefit selected patients with type II ovarian carcinoma harboring KRAS/MAPK1 amplifications. 23820584

2013

Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0029925
Disease: Ovarian Carcinoma
Ovarian Carcinoma
0.470 GeneticVariation BEFREE Mutations in the KRAS gene are one of the most frequent genetic abnormalities in ovarian carcinoma. 19358724

2009

Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0029925
Disease: Ovarian Carcinoma
Ovarian Carcinoma
0.470 GeneticVariation BEFREE The apparent restriction of these BRAF and KRAS mutations to low-grade serous ovarian carcinoma and its precursors suggests that low-grade and high-grade ovarian serous carcinomas develop through independent pathways. 12644542

2003

Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0029925
Disease: Ovarian Carcinoma
Ovarian Carcinoma
0.470 GeneticVariation BEFREE Role of KRAS and BRAF gene mutations in mucinous ovarian carcinoma. 12893203

2003

Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0029925
Disease: Ovarian Carcinoma
Ovarian Carcinoma
0.470 GeneticVariation BEFREE Thus, K-RAS mutations at codon 12 and 6q27 LOH were suggested to be involved in the development and/or progression of mucinous ovarian carcinoma and serous ovarian carcinoma, respectively. 10748293

2000

Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0029925
Disease: Ovarian Carcinoma
Ovarian Carcinoma
0.470 AlteredExpression BEFREE This suggests that mutation of the nm23 genes and the K-ras gene affects carcinogenesis or progression of ovarian carcinoma by modulating expression of the nm23 genes. 7669582

1995

Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0029925
Disease: Ovarian Carcinoma
Ovarian Carcinoma
0.470 GeneticVariation BEFREE A cell line from a human ovarian carcinoma with amplification of the K-ras gene. 3756872

1986

Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0029925
Disease: Ovarian Carcinoma
Ovarian Carcinoma
0.470 CausalMutation CGI

Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0029925
Disease: Ovarian Carcinoma
Ovarian Carcinoma
0.470 Biomarker HPO