×
Entrez Id: 3569
Gene Symbol: IL6
IL6
Unipolar Depression
0.600
Biomarker
BEFREE
Some researchers suggested that the elevation of interleukin-6 (IL6 ) correlates with major depression and PTSD.
31291232 2019
×
Entrez Id: 3569
Gene Symbol: IL6
IL6
Unipolar Depression
0.600
GeneticVariation
BEFREE
Sex difference in IL-6 modulation of cognition among Chinese individuals with major depressive disorder .
31629608 2019
×
Entrez Id: 3569
Gene Symbol: IL6
IL6
Unipolar Depression
0.600
AlteredExpression
BEFREE
Plasma levels of IL-6 and INF-γ and lipid profile, including total cholesterol (TC), triglycerides (TGs), low-density lipoproteins (LDLs), and high-density lipoproteins, were measured in 60 patients meeting criteria of the fifth version of the Diagnostic and Statistical Manual of Mental Disorders for Major Depression (22 patients who attempted suicide and 38 patients who did not attempt suicide) and 30 healthy controls.
30844329 2019
×
Entrez Id: 3569
Gene Symbol: IL6
IL6
Unipolar Depression
0.600
AlteredExpression
BEFREE
These gray matter volume differences between bipolar disorder and unipolar depression were negatively correlated with soluble IL-6 receptor levels.
30359810 2019
×
Entrez Id: 3569
Gene Symbol: IL6
IL6
Unipolar Depression
0.600
AlteredExpression
BEFREE
The level of IL-6 was associated with sleep disturbances in patients with major depressive disorder .
31417262 2019
×
Entrez Id: 3569
Gene Symbol: IL6
IL6
Unipolar Depression
0.600
AlteredExpression
BEFREE
Plasma levels of IL-6 in patients with untreated major depressive disorder : comparison with catecholamine metabolites.
31686824 2019
×
Entrez Id: 3569
Gene Symbol: IL6
IL6
Unipolar Depression
0.600
Biomarker
BEFREE
While cross-sectional associations of inflammatory markers interleukin-6 (IL-6 ) and C-reactive protein with major depressive disorder are well established, evidence for longitudinal associations mostly comes from studies on depression symptoms, not diagnoses.
30819515 2019
×
Entrez Id: 3569
Gene Symbol: IL6
IL6
Unipolar Depression
0.600
Biomarker
BEFREE
Higher concentration of interleukin 6 - A possible link between major depressive disorder and childhood abuse.
29626828 2018
×
Entrez Id: 3569
Gene Symbol: IL6
IL6
Unipolar Depression
0.600
AlteredExpression
BEFREE
Association between increased serum interleukin-6 levels and sustained attention deficits in patients with major depressive disorder .
29415791 2018
×
Entrez Id: 3569
Gene Symbol: IL6
IL6
Unipolar Depression
0.600
AlteredExpression
BEFREE
A PubMed/Medline database search was performed using the following search terms: sirukumab; anti-IL-6; IL-6 ; major depressive disorder ; inflammation.
27913990 2017
×
Entrez Id: 3569
Gene Symbol: IL6
IL6
Unipolar Depression
0.600
Biomarker
BEFREE
Influence of fluvoxamine on plasma interleukin-6 or clinical improvement in patients with major depressive disorder .
28243095 2017
×
Entrez Id: 3569
Gene Symbol: IL6
IL6
Unipolar Depression
0.600
AlteredExpression
BEFREE
The plasma level of IL-6 increased in patients with BD and MD .
28074937 2017
×
Entrez Id: 3569
Gene Symbol: IL6
IL6
Unipolar Depression
0.600
AlteredExpression
BEFREE
Changes in interleukin-6 levels during electroconvulsive therapy may reflect the therapeutic response in major depression .
27858966 2017
×
Entrez Id: 3569
Gene Symbol: IL6
IL6
Unipolar Depression
0.600
AlteredExpression
BEFREE
Major depressive disorder is a condition associated with dysregulated cytokine levels; among these, IL6 .27796193 2017
×
Entrez Id: 3569
Gene Symbol: IL6
IL6
Unipolar Depression
0.600
Biomarker
BEFREE
An altered peripheral IL6 response in major depressive disorder .
26804030 2016
×
Entrez Id: 3569
Gene Symbol: IL6
IL6
Unipolar Depression
0.600
Biomarker
BEFREE
Identification of IL6 as a susceptibility gene for major depressive disorder .
27502736 2016
×
Entrez Id: 3569
Gene Symbol: IL6
IL6
Unipolar Depression
0.600
Biomarker
BEFREE
Genetic variation in IL-1β, IL-2, IL-6 , TSPO and BDNF and response to duloxetine or placebo treatment in major depressive disorder .
26556688 2015
×
Entrez Id: 3569
Gene Symbol: IL6
IL6
Unipolar Depression
0.600
Biomarker
PSYGENET
We confirmed a similar elevation of serum IL-6 in two separate cohorts of patients with treatment-resistant major depressive disorder .
25331895 2014
×
Entrez Id: 3569
Gene Symbol: IL6
IL6
Unipolar Depression
0.600
AlteredExpression
BEFREE
Plasma levels of interleukin-6 and selective serotonin reuptake inhibitor response in patients with major depressive disorder .
23813968 2013
×
Entrez Id: 3569
Gene Symbol: IL6
IL6
Unipolar Depression
0.600
Biomarker
PSYGENET
Plasma levels of interleukin-6 and selective serotonin reuptake inhibitor response in patients with major depressive disorder .
23813968 2013
×
Entrez Id: 3569
Gene Symbol: IL6
IL6
Unipolar Depression
0.600
AlteredExpression
BEFREE
Reduced expression of glucocorticoid-inducible genes GILZ and SGK-1: high IL-6 levels are associated with reduced hippocampal volumes in major depressive disorder .
22832853 2012
×
Entrez Id: 3569
Gene Symbol: IL6
IL6
Unipolar Depression
0.600
Biomarker
PSYGENET
Tryptophan depletion in depressed patients occurs independent of kynurenine pathway activation.
22683764 2012
×
Entrez Id: 3569
Gene Symbol: IL6
IL6
Unipolar Depression
0.600
Biomarker
PSYGENET
Reduced expression of glucocorticoid-inducible genes GILZ and SGK-1: high IL-6 levels are associated with reduced hippocampal volumes in major depressive disorder .
22832853 2012
×
Entrez Id: 3569
Gene Symbol: IL6
IL6
Unipolar Depression
0.600
Biomarker
PSYGENET
Leukocyte telomere length in major depression: correlations with chronicity, inflammation and oxidative stress--preliminary findings.
21448457 2011
×
Entrez Id: 3569
Gene Symbol: IL6
IL6
Unipolar Depression
0.600
Biomarker
CTD_human
Functional polymorphisms in the interleukin-6 and serotonin transporter genes, and depression and fatigue induced by interferon-alpha and ribavirin treatment.
18458677 2009