Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
CUI: C0153349
Disease: Malignant neoplasm of tongue
Malignant neoplasm of tongue 		0.050 Biomarker BEFREE <i>In vitro</i> antitumor effects of FGFR and PI3K inhibitors on human papillomavirus positive and negative tonsillar and base of tongue cancer cell lines. 31788102

2019
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
CUI: C0153349
Disease: Malignant neoplasm of tongue
Malignant neoplasm of tongue 		0.050 Biomarker BEFREE Alterations in ANO1, NUDCD1, PIK3CA defined survival in tongue cancer patients with nodal metastasis (node+ECS-), while EPS8 is a significant differential in node+ECS- laryngopharyngeal cancers. 31310629

2019
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
CUI: C0153349
Disease: Malignant neoplasm of tongue
Malignant neoplasm of tongue 		0.050 Biomarker BEFREE Taken together, our study suggested ITGA3 may facilitate the development of TC via activating PI3K-Akt signaling pathway. 30128883

2018
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
CUI: C0153349
Disease: Malignant neoplasm of tongue
Malignant neoplasm of tongue 		0.050 GeneticVariation BEFREE Differences in mutation frequency of TP53 and PIK3CA were found between HPV+ TSCC/BOTSCC and HNCUP and HPV- TSCC/BOTSCC. 28525363

2017
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
CUI: C0153349
Disease: Malignant neoplasm of tongue
Malignant neoplasm of tongue 		0.050 Biomarker BEFREE Our study highlights critical roles for PIK3CA in the tongue cancer, and suggests that PIK3CA gene might be considered as a therapeutic target for clinical tongue cancer. 22812189

2011