Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
CUI: C0162810
Disease: Cicatrix, Hypertrophic
Cicatrix, Hypertrophic
0.030 Biomarker BEFREE MicroRNA-494 targets PTEN and suppresses PI3K/AKT pathway to alleviate hypertrophic scar formation. 31069607

2019

Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
CUI: C0162810
Disease: Cicatrix, Hypertrophic
Cicatrix, Hypertrophic
0.030 Biomarker BEFREE Transcriptome sequencing showed that PTX affects HS formation through the PI3K/Akt/FoxO1 signalling pathway to activate p27<sup>Kip1</sup> . 31270945

2019

Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
CUI: C0162810
Disease: Cicatrix, Hypertrophic
Cicatrix, Hypertrophic
0.030 Biomarker LHGDN Angiotensin II regulates phosphoinositide 3 kinase/Akt cascade via a negative crosstalk between AT1 and AT2 receptors in skin fibroblasts of human hypertrophic scars. 16522324

2006