Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0205969
Disease: Thymic Carcinoma
Thymic Carcinoma 		0.560 Biomarker BEFREE Mutations in the EGFR pathway and TP53 in thymic carcinoma may be frequent, and the EGFR pathway mutations may be associated with a poor prognosis in thymic squamous cell carcinoma patients. 31179560

2019
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0205969
Disease: Thymic Carcinoma
Thymic Carcinoma 		0.560 GeneticVariation BEFREE TP53 was the most frequently mutated gene in TETs (n = 13; 17%), especially in TCs (26%), and was associated with a poorer overall survival (p < 0.0001). 25482724

2014
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0205969
Disease: Thymic Carcinoma
Thymic Carcinoma 		0.560 Biomarker CTD_human Notably, we identified recurrent mutations of known cancer genes, including TP53, CYLD, CDKN2A, BAP1 and PBRM1, in thymic carcinomas. 24974848

2014
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0205969
Disease: Thymic Carcinoma
Thymic Carcinoma 		0.560 GeneticVariation BEFREE There were no p53 gene mutations in 15 invasive thymoma, although one of four (25%) thymic carcinomas showed two point mutations. p53 gene alterations seem to be associated with malignant activity of tumor cells, and therefore detection of p53 gene mutations is useful as a diagnostic factor. 9852302

1998
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0205969
Disease: Thymic Carcinoma
Thymic Carcinoma 		0.560 Biomarker BEFREE In non-organotypic thymic carcinomas p53 was detected with both antibodies. 9247629

1997
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0205969
Disease: Thymic Carcinoma
Thymic Carcinoma 		0.560 GeneticVariation BEFREE Subsequently, we examined the 36 thymomas and 4 thymic carcinomas for mutations in p53 and CDKN2 genes, using PCR-SSCP and direct-sequencing analyses. 9398039

1997
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0205969
Disease: Thymic Carcinoma
Thymic Carcinoma 		0.560 Biomarker BEFREE There was significant difference in p53 protein immunopositivity between thymic carcinoma and each of the noninvasive or invasive/metastatic thymomas. 7572785

1995
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0205969
Disease: Thymic Carcinoma
Thymic Carcinoma 		0.560 GenomicAlterations CGI

Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0205969
Disease: Thymic Carcinoma
Thymic Carcinoma 		0.560 CausalMutation CGI