Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4361
Gene Symbol: MRE11
MRE11
CUI: C1140680
Disease: Malignant neoplasm of ovary
Malignant neoplasm of ovary
0.320 AlteredExpression BEFREE Frequent lack of MRE11, RAD50, NBS1 protein detection in type I human ovarian carcinomas is observed in EOC and our data suggests further investigation regarding sensitivity to PARP-inhibition in tumours lacking MRE11 expression. 28073364

2017

Entrez Id: 4361
Gene Symbol: MRE11
MRE11
CUI: C1140680
Disease: Malignant neoplasm of ovary
Malignant neoplasm of ovary
0.320 GeneticVariation BEFREE Thirty-one percent of ovarian carcinomas had a deleterious germline (24%) and/or somatic (9%) mutation in one or more of the 13 homologous recombination genes: BRCA1, BRCA2, ATM, BARD1, BRIP1, CHEK1, CHEK2, FAM175A, MRE11A, NBN, PALB2, RAD51C, and RAD51D. 24240112

2014

Entrez Id: 4361
Gene Symbol: MRE11
MRE11
CUI: C1140680
Disease: Malignant neoplasm of ovary
Malignant neoplasm of ovary
0.320 GeneticVariation UNIPROT