Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5218
Gene Symbol: CDK14
CDK14
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.470 Biomarker BEFREE In conclusion, it was implied that LINC00707 can lead to HCC progression through sponging miR-206 and modulating CDK14. 30488589

2019

Entrez Id: 5218
Gene Symbol: CDK14
CDK14
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.470 Biomarker BEFREE MiR-877-5p suppresses cell growth, migration and invasion by targeting cyclin dependent kinase 14 and predicts prognosis in hepatocellular carcinoma. 29863248

2018

Entrez Id: 5218
Gene Symbol: CDK14
CDK14
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.470 GeneticVariation GWASCAT Genome-Wide Association Study Identifies a New Locus at 7q21.13 Associated with Hepatitis B Virus-Related Hepatocellular Carcinoma. 29246937

2018

Entrez Id: 5218
Gene Symbol: CDK14
CDK14
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.470 AlteredExpression BEFREE The serine/threonine-protein kinase PFTAIRE 1 (PFTK1) is a member of the cyclin‑dependent kinase family that is highly expressed in several malignant tumors, including hepatocellular carcinoma, esophageal, breast and gastric cancers, and glioma. 28498444

2017

Entrez Id: 5218
Gene Symbol: CDK14
CDK14
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.470 AlteredExpression BEFREE Recent studies show that PFTK1 is highly expressed in several malignant tumors such as hepatocellular carcinoma, esophageal cancer, breast cancer, and involved in regulation of cell cycle, tumors proliferation, migration, and invasion that further influence the prognosis of tumors. 26488471

2015

Entrez Id: 5218
Gene Symbol: CDK14
CDK14
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.470 Biomarker CTD_human The results suggest that seven of these genes, including VCAM1 and CDK14, may confer growth and infiltration capacity to HCC cells. 22922871

2012

Entrez Id: 5218
Gene Symbol: CDK14
CDK14
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.470 AlteredExpression BEFREE Here, we showed from tissue microarray that common upregulations of PFTK1 in primary HCC tumors (n=133/180) correlated significantly with early age onset (40 years), advance tumor grading and presence of microvascular invasion (P0.05). 21577206

2011

Entrez Id: 5218
Gene Symbol: CDK14
CDK14
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.470 Biomarker BEFREE Our study stemmed from an earlier investigation where we demonstrated that PFTK1 kinase conferred cell migratory advantages in human hepatocellular carcinoma (HCC) cells. 21184254

2011

Entrez Id: 5218
Gene Symbol: CDK14
CDK14
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.470 Biomarker BEFREE Quantitative reverse transcription (RT)-PCR evaluation further indicated upregulation of a single candidate gene, PFTK1, that correlated significantly with both advanced metastatic HCCs (P = 0.032) and tumor microvascular invasion (P = 0.012). 17559150

2007