Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
CUI: C2931367
Disease: Thyroid cancer, follicular
Thyroid cancer, follicular
0.030 Biomarker BEFREE Downregulated miR-21 mediates matrine-induced apoptosis via the PTEN/Akt signaling pathway in FTC-133 human follicular thyroid cancer cells. 31579406

2019

Entrez Id: 5728
Gene Symbol: PTEN
PTEN
CUI: C2931367
Disease: Thyroid cancer, follicular
Thyroid cancer, follicular
0.030 GeneticVariation BEFREE CS/CS-like patients have elevated risks of follicular thyroid cancer due to PTEN pathogenic mutations and of papillary thyroid cancer from SDHx and KLLN alterations. 21956414

2011

Entrez Id: 5728
Gene Symbol: PTEN
PTEN
CUI: C2931367
Disease: Thyroid cancer, follicular
Thyroid cancer, follicular
0.030 PosttranslationalModification BEFREE The authors found PTEN methylation to become progressively higher from benign thyroid adenoma to follicular thyroid cancer and to aggressive anaplastic thyroid cancer, which harbored activating genetic alterations in the PI3K/AKT pathway correspondingly with a progressively higher prevalence. 18831514

2008