Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 10239
Gene Symbol: AP3S2
AP3S2
Diabetes Mellitus, Non-Insulin-Dependent
0.440 GeneticVariation BEFREE We performed a replication study to investigate the association of these susceptibility loci with T2DM in the Chinese population.We genotyped 1968 Chinese participants (996 with T2DM and 972controls) for rs8191974 in Gas6 and rs2028299 near Ap3s2, and examined their association with T2DM using a logistic regression analysis. 28399188

2017

Entrez Id: 10239
Gene Symbol: AP3S2
AP3S2
Diabetes Mellitus, Non-Insulin-Dependent
0.440 Biomarker BEFREE At six loci with genome-wide evidence for T2D association (AP3S2, KCNK16, NOTCH2, SCL30A8, VPS26A, and WFS1) predicted mRNA target sites for islet-expressed miRNAs overlapped potentially causal variants. 23372846

2013

Entrez Id: 10239
Gene Symbol: AP3S2
AP3S2
Diabetes Mellitus, Non-Insulin-Dependent
0.440 GeneticVariation BEFREE We genotyped 11,319 Japanese participants (8,318 with type 2 diabetes and 3,001 controls) for each of the 7 SNPs-rs5945326 near DUSP9, rs3923113 near GRB14, rs16861329 in ST6GAL1, rs1802295 in VPS26A, rs7178572 in HMG20A, rs2028299 near AP3S2, and rs4812829 in HNF4A-and examined the association of each of these 7 SNPs with type 2 diabetes by using logistic regression analysis. 23029454

2012

Entrez Id: 10239
Gene Symbol: AP3S2
AP3S2
Diabetes Mellitus, Non-Insulin-Dependent
0.440 Biomarker BEFREE In the combined analysis, we identified common genetic variants at six loci (GRB14, ST6GAL1, VPS26A, HMG20A, AP3S2 and HNF4A) newly associated with T2D (P = 4.1 × 10(-8) to P = 1.9 × 10(-11)). 21874001

2011