Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 208
Gene Symbol: AKT2
AKT2
Diabetes Mellitus, Non-Insulin-Dependent
0.960 Biomarker BEFREE Akt2 (Protein Kinase B Beta) Stabilizes ATP7A, a Copper Transporter for Extracellular Superoxide Dismutase, in Vascular Smooth Muscle: Novel Mechanism to Limit Endothelial Dysfunction in Type 2 Diabetes Mellitus. 29301787

2018

Entrez Id: 208
Gene Symbol: AKT2
AKT2
Diabetes Mellitus, Non-Insulin-Dependent
0.960 AlteredExpression BEFREE Newer drug targets such as protein kinase B (Akt/PKB), AMP-activated protein kinase (AMPK), sirtuin (SIRT), and others are novel approaches that act via different mechanisms and possibly treating T2DM of distinct variations and aetiologies. 29696964

2018

Entrez Id: 208
Gene Symbol: AKT2
AKT2
Diabetes Mellitus, Non-Insulin-Dependent
0.960 GeneticVariation BEFREE In this study, we aimed to test whether polymorphisms in the PIK3CA (catalytic subunit of PI3K), AKT1, AKT2, and FRAP1 (mTOR) genes were associated with the risk of type 2 diabetes mellitus (T2DM) among Chinese population. 28477532

2017

Entrez Id: 208
Gene Symbol: AKT2
AKT2
Diabetes Mellitus, Non-Insulin-Dependent
0.960 Biomarker BEFREE AKT2 is closely linked to Type II diabetes and the implications of various types of mutations are discussed. 24039187

2013

Entrez Id: 208
Gene Symbol: AKT2
AKT2
Diabetes Mellitus, Non-Insulin-Dependent
0.960 Biomarker BEFREE In order to determine whether the Akt2 gene plays a role in the pathogenesis of type 2 diabetes characterized by insulin resistance, and to further identify if variations in this gene have a relationship with type 2 diabetes, we sequenced the entire coding region and splice junctions of Akt2 and made a further case-control study to explore the association between single-nucleotide polymorphisms (SNPs) in this gene and type 2 diabetes in the Chinese Han population. 21518566

2011

Entrez Id: 208
Gene Symbol: AKT2
AKT2
Diabetes Mellitus, Non-Insulin-Dependent
0.960 GeneticVariation BEFREE Furthermore, genetic variation in and around the AKT2 locus is unlikely to contribute significantly to the risk of type 2 diabetes or related intermediate metabolic traits in U.K. populations. 17327441

2007