Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
CUI: C0023418
Disease: leukemia
leukemia
0.400 GeneticVariation BEFREE Additionally, GSTM1 null genotype was also significantly correlated with elevated individual susceptibility to leukemia in East Asians. 30659796

2019

Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
CUI: C0023418
Disease: leukemia
leukemia
0.400 GeneticVariation BEFREE The results suggest that regular daily green tea consumption may reduce leukemia risk in Chinese adults regardless of GSTM1 and GSTP1 polymorphic status. 26578531

2017

Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
CUI: C0023418
Disease: leukemia
leukemia
0.400 GeneticVariation BEFREE In this study, GST gene mutations including GSTM1 and GSTT1 were evaluated in patients with leukemia. 23444902

2013

Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
CUI: C0023418
Disease: leukemia
leukemia
0.400 GeneticVariation BEFREE Genetic polymorphisms of metabolic enzymes CYP1A1, CYP2D6, GSTM1 and GSTT1 and leukemia susceptibility. 18414197

2008

Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
CUI: C0023418
Disease: leukemia
leukemia
0.400 GeneticVariation BEFREE The work studied possible association between genetic polymorphisms of CYP2D6, GSTM1, GSTT1and NQO1 and altered susceptibility to leukaemia, correlating these genetic polymorphisms with clinical prognostic data, response to therapy and relapse. 17581325

2007

Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
CUI: C0023418
Disease: leukemia
leukemia
0.400 GeneticVariation BEFREE The most notable findings are: GSTM1 deletion and bladder cancer risk [odds ratio (OR) = 1.60; 95% confidence interval 1.00-2.56]; CYP1A1 and leukemia (2.22, 1.33-3.70; heterozygotes); CYP1B1 and leukemia (0.47, 0.27-0.84; homozygotes); MnSOD and leukemia (1.91, 1.08-3.38; homozygotes) and NQO1 and lung cancer (8.03, 1.73-37.3; homozygotes). 17496311

2007

Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
CUI: C0023418
Disease: leukemia
leukemia
0.400 GeneticVariation BEFREE Maternal smoking during pregnancy was not related to leukaemia, but an interaction was observed in the case-only analysis with CYP1A1*2A variant allele (odds ratio (OR) 2.2 [1.0-4.9]) and with GSTM1 deletion (OR 2.3 [1.2-4.4]). 16284498

2005

Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
CUI: C0023418
Disease: leukemia
leukemia
0.400 GeneticVariation BEFREE Analysis of the GSTM1 and NAT2 polymorphisms failed to show an association with any of the neoplasias, although a near significant increase in fast acetylators was also found in the leukaemia group (50.0 versus 35.9%, P = 0.06). 10383893

1999