DisGeNET - a database of gene-disease associations

Source: BEFREE

Disease: Malignant neoplasm of stomach ×

Gene: ADAM10 ×

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Gene

Disease

Score _gda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

Entrez Id:	102
Gene Symbol:	ADAM10

ADAM10

CUI:	C0024623
Disease:	Malignant neoplasm of stomach

Malignant neoplasm of stomach

0.030

AlteredExpression

BEFREE

EphA8 acts as an oncogene and contributes to poor prognosis in gastric cancer via regulation of ADAM10.

31026069

2019

Entrez Id:	102
Gene Symbol:	ADAM10

ADAM10

CUI:	C0024623
Disease:	Malignant neoplasm of stomach

Malignant neoplasm of stomach

0.030

Biomarker

BEFREE

ADAM10 was a direct target of miR‑320a in GC.

29152656

2017

Entrez Id:	102
Gene Symbol:	ADAM10

ADAM10

CUI:	C0024623
Disease:	Malignant neoplasm of stomach

Malignant neoplasm of stomach

0.030

AlteredExpression

BEFREE

Furthermore, the expression level of miR-448 was negatively correlated with the expression level of ADAM10 in GC tissues.

26852749

2016