Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3659
Gene Symbol: IRF1
IRF1
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.660 Biomarker BEFREE MTMR2 mediated EMT through the IFNγ/STAT1/IRF1 pathway to promote GC invasion and metastasis. 31113461

2019

Entrez Id: 3659
Gene Symbol: IRF1
IRF1
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.660 Biomarker BEFREE MIR17HG-miR-18a/19a axis, regulated by interferon regulatory factor-1, promotes gastric cancer metastasis via Wnt/β-catenin signalling. 31186404

2019

Entrez Id: 3659
Gene Symbol: IRF1
IRF1
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.660 GeneticVariation BEFREE SNP rs56288038 (C/G) in IRF-1 3'UTR was involved in the occurrence of GC by acting as a tumor promoter factor. 27866197

2016

Entrez Id: 3659
Gene Symbol: IRF1
IRF1
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.660 Biomarker BEFREE We used these clones and recombinant adenovirus expressing IRF-1 to explore the mechanism of IRF-1-induced apoptosis in gastric cancer. 19851330

2010

Entrez Id: 3659
Gene Symbol: IRF1
IRF1
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.660 GeneticVariation BEFREE The interferon regulatory factor-1 (IRF1) gene, localized on chromosome 5q31.1, is mutated or rearranged in several cancers including some hematopoietic and gastric cancers. 19697121

2010

Entrez Id: 3659
Gene Symbol: IRF1
IRF1
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.660 Biomarker BEFREE These results suggest that the loss of functional IRF-1 is critical for the development of human gastric cancers. 9679752

1998