Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.070 Biomarker BEFREE A specific phosphoinositide 3-kinase (PI3K) inhibitor, wortmannin, was used to test the effect of PI3K inhibition on the secretion of CCL-2 in gastric cancer. 29422964

2018

Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.070 Biomarker BEFREE CCL2-SQSTM1 positive feedback loop suppresses autophagy to promote chemoresistance in gastric cancer. 29989092

2018

Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.070 Biomarker BEFREE The exactly mechanism between CCL2 and Snail in the process of EMT in GC need further investigation. 28215642

2017

Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.070 AlteredExpression BEFREE IFN-γ and IL-10 levels were significantly higher in early (I/II) and late stage (III/IV) gastric cancer; IL-1β and IL-8 were higher and MCP-1 was lower only in late stage (IV) patients. 28558708

2017

Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.070 GeneticVariation BEFREE Our study provides the first evidence that the NFKB1 rs230510 and CCL2 rs4586 are significantly associated with the clinical outcome in patients with locoregional gastric cancer. 25411415

2015

Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.070 GeneticVariation BEFREE Our data suggest that the genetic polymorphism CCL2 A-2518G may not only be associated with an increased risk of gastric cancer, but also with advanced stage of gastric cancer in the Chinese population. 21107756

2011

Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.070 AlteredExpression BEFREE CD40L and MCP-1 mRNA levels were significantly higher in poorly differentiated gastric cancers than in H. pylori-infected gastritis patients. 18373164

2008