Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1728
Gene Symbol: NQO1
NQO1
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma
0.350 GeneticVariation BEFREE We examined risk of multiple myeloma (MM) associated with variants in genes involved in metabolism and response to exogenous chemicals [cytochrome P450 enzymes (CYP1B1, CYP2C9), epoxide hydrolase (EPHX1), paraoxonase 1 (PON1), arylhydrocarbon hydroxylase receptor (AHR), and NAD(P)H:quinone oxidoreductase (NQO1)]. 19736056

2009

Entrez Id: 1728
Gene Symbol: NQO1
NQO1
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma
0.350 GeneticVariation BEFREE We had previously reported the association of the NQO1*2/*2 polymorphism with a decreased risk for multiple myeloma (MM) in Koreans (odds ratio, OR, 0.24; 95% confidence interval, CI, 0.01-0.68). 18285692

2008

Entrez Id: 1728
Gene Symbol: NQO1
NQO1
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma
0.350 GeneticVariation BEFREE Individual genotypes of 128 patients affected by multiple myeloma and 245 healthy controls were determined and our results do not support any major role of NQO1 or GSTP1 polymorphisms in multiple myeloma pathogenesis. 18061666

2008

Entrez Id: 1728
Gene Symbol: NQO1
NQO1
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma
0.350 GeneticVariation BEFREE Individuals who carried polymorphisms for GSTT1 null and/or high activity microsomal epoxide hydrolase (mEH 113YY+139HR or 113YY+139RR or 113YH+139RR) and/or low activity NAD(P)H:quinone oxidoreductase 1 (NQO1 187PS/SS) were 1.65, 2.49 and 13 times more likely to have MM (P(trend)=0.001). 16949155

2007