Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 100133941
Gene Symbol: CD24
CD24
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.100 Biomarker BEFREE CD44+/CD24‑/low is currently the most commonly used marker for breast cancer stem cells (CSCs), which are considered the main cause of drug resistance, relapse and metastasis. 31545416

2019

Entrez Id: 100133941
Gene Symbol: CD24
CD24
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.100 Biomarker BEFREE The results revealed that the expression of NY-ESO-1/CD44/CD24 was associated with breast cancer metastasis. 31579408

2019

Entrez Id: 100133941
Gene Symbol: CD24
CD24
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.100 AlteredExpression BEFREE Moreover, the expression of CD24, the Siglec-10 ligand, was associated with tumor stage and cancer cell metastasis. 31534365

2019

Entrez Id: 100133941
Gene Symbol: CD24
CD24
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.100 Biomarker BEFREE Among these stemness markers, we identified CD24 as a key driver of tumorigenesis and metastasis in vivo. 30467381

2019

Entrez Id: 100133941
Gene Symbol: CD24
CD24
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.100 AlteredExpression BEFREE The expression of CD24 slightly correlated with lymphovascular invasion (<i>p</i>=0.04), whereas CD133 was associated with distant metastasis. 31213893

2019

Entrez Id: 100133941
Gene Symbol: CD24
CD24
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.100 AlteredExpression BEFREE The CD24 expression is associated with the development, invasion, and metastasis of cancer cells. 30317611

2019

Entrez Id: 100133941
Gene Symbol: CD24
CD24
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.100 AlteredExpression BEFREE The expressions of CD24, B7-H4 and PCNA have correlations with the occurrence, development, invasion and metastasis of ovarian cancer, and the combined detection may have clinical guiding significance for early diagnosis of ovarian cancer and screening of high-risk patients. 31128028

2019

Entrez Id: 100133941
Gene Symbol: CD24
CD24
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.100 Biomarker BEFREE To clarify the role of CD24 in bone metastasis, we intracardially injected CD24-knockdown HARA-B4 cells into mice and monitored metastasis through detection of iRFP720 using an in vivo imaging system. 29095550

2018

Entrez Id: 100133941
Gene Symbol: CD24
CD24
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.100 Biomarker BEFREE Author Correction: Unraveling the roles of CD44/CD24 and ALDH1 as cancer stem cell markers in tumorigenesis and metastasis. 29511206

2018

Entrez Id: 100133941
Gene Symbol: CD24
CD24
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.100 AlteredExpression BEFREE CD24 (cluster of differentiation 24) is a small heavy glycosylated protein, which is overexpressed in many cancer and some cancer stem cells and is associated with the development, invasion, and metastasis of cancer cells. 28820056

2018

Entrez Id: 100133941
Gene Symbol: CD24
CD24
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.100 AlteredExpression BEFREE CD24 is expressed in benign and malignant solid tumors and is also involved in cell adhesion and metastasis. 29693159

2018

Entrez Id: 100133941
Gene Symbol: CD24
CD24
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.100 Biomarker BEFREE CD24 was significantly associated with tumor differentiation, but was not correlated with other clinicopathologic parameters including gender, age, tumor size, tumor number, capsulation status, HBsAg status, tumor node metastasis stage, ALT, AFP, and GGT level. 30543135

2018

Entrez Id: 100133941
Gene Symbol: CD24
CD24
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.100 AlteredExpression BEFREE The present study aimed to explore the role of the combination of Twist1 expression in metastasized ALN and the serum level of CA15‑3 in evaluating the prognosis of patients with breast cancer. cluster of differentiation (CD)44, CD24, aldehyde dehydrogenase (ALDH)1 and Twist1 expression in normal and metastasized ALN from 102 patients with breast cancer were detected using laser confocal microscopy and the expression of the genes evaluated by reverse transcription‑quantitative polymerase chain reaction; E‑cadherin, N‑cadherin and vimentin expression was also tested by western blotting. 28112378

2017

Entrez Id: 100133941
Gene Symbol: CD24
CD24
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.100 Biomarker BEFREE Our results demonstrate that inhibition of EP4 attenuates the RCC intravasation and metastasis by downregulating CD24 and that P-selectin participates in tumor intravasation, implying a potential for these molecules as therapeutic targets for advanced RCC treatment. 28104442

2017

Entrez Id: 100133941
Gene Symbol: CD24
CD24
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.100 Biomarker BEFREE Unraveling the roles of CD44/CD24 and ALDH1 as cancer stem cell markers in tumorigenesis and metastasis. 29062075

2017

Entrez Id: 100133941
Gene Symbol: CD24
CD24
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.100 Biomarker BEFREE In the current study, we tested the hypothesis that these ALDHhiCD44+CD24- breast cancer cells interact with factors in the bone secondary organ microenvironment to facilitate metastasis. 28498874

2017

Entrez Id: 100133941
Gene Symbol: CD24
CD24
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.100 AlteredExpression BEFREE However, CD24 expression had no correlation with tumor size, tumor grade, distance metastasis, estrogen receptor (ER) status, progesterone receptor (PR) status, or HER2 status. 28315505

2017

Entrez Id: 100133941
Gene Symbol: CD24
CD24
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.100 AlteredExpression BEFREE Breast cancer stem cells (BCSC) have been identified in breast carcinoma as CD44(+)/CD24(-/low) cells, which display tumorigenic activity and have the ability to self-renew, differentiate and metastasize. 27259689

2016

Entrez Id: 100133941
Gene Symbol: CD24
CD24
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.100 AlteredExpression BEFREE Our data showed that the microvessal density (MVD) was related to the expression of CD24 in primary and metastasis CRC. 27494878

2016

Entrez Id: 100133941
Gene Symbol: CD24
CD24
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.100 Biomarker BEFREE Here we show that both targeted mutation and short hairpin RNA (shRNA) silencing of CD24 retard the growth, progression and metastasis of prostate cancer. 25600590

2015

Entrez Id: 100133941
Gene Symbol: CD24
CD24
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.100 Biomarker BEFREE These findings indicate that CD24(+) cells play a role in tumor migration and metastasis and support JAK2 as a therapeutic target in ovarian cancer. 25969154

2015

Entrez Id: 100133941
Gene Symbol: CD24
CD24
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.100 Biomarker BEFREE These results demonstrate functional roles for two different pathways, CD24-dependent and Yap/Taz-dependent pathways, in lung tumor propagation and metastasis. 24497554

2014

Entrez Id: 100133941
Gene Symbol: CD24
CD24
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.100 Biomarker BEFREE CD24 is a hepatic cancer stem cell biomarker that is closely associated with apoptosis, metastasis and recurrence of hepatocellular carcinoma (HCC). 24488178

2014

Entrez Id: 100133941
Gene Symbol: CD24
CD24
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.100 Biomarker BEFREE CD24, as a cell surface marker for detecting pancreatic cancer stem cells (CSCs), is directly correlated with the development and metastasis of pancreatic cancer. 23679566

2013

Entrez Id: 100133941
Gene Symbol: CD24
CD24
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.100 AlteredExpression BEFREE The aforementioned findings offer convincing evidence for the first time that the increased expression of CD24 is correlated with tumor aggressiveness and tumor metastasis of osteosarcoma, and this molecule is an independent prognostic marker for osteosarcoma patients. 23143956

2013