Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 31
Gene Symbol: ACACA
ACACA
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.070 Biomarker BEFREE The current study aimed to investigate the role of MYB in salivary (S)ACC growth and metastasis. 30896785

2019

Entrez Id: 31
Gene Symbol: ACACA
ACACA
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.070 AlteredExpression BEFREE We discovered that: (1) differentially expressed (DE) mRNAs and DE miRNAs are potentially involved in SACC metastasis; (2) multiple regulatory interactions between DE miRNAs and DE mRNAs exist; and (3) miR-338-5p/3p target LAMC2 to impair motility and invasion of ACC-M and MDA-MB-231 cells. 29678584

2018

Entrez Id: 31
Gene Symbol: ACACA
ACACA
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.070 Biomarker BEFREE ACC1 phosphorylation was mediated by TGFβ-activated kinase (TAK) 1, and ACC1 inhibition was indispensable for the elevation of cellular acetyl-CoA, the subsequent increase in Smad2 transcription factor acetylation and activation, and ultimately epithelial-mesenchymal transition and metastasis induction. 29056512

2017

Entrez Id: 31
Gene Symbol: ACACA
ACACA
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.070 Biomarker BEFREE ACC is a low-grade malignant tumor with poor prognosis and high recurrence and metastases. 26261681

2015

Entrez Id: 31
Gene Symbol: ACACA
ACACA
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.070 AlteredExpression BEFREE We found decreased effects on the proliferation phenotype of ACC-M cell in vivo and in vitro with XAGE-1b downregulation, and XAGE-1b overexpression promoted the proliferation of ACC-2 cells in vivo and in vitro, while its overexpression promoted the transmembrane invasion of ACC-2 cells in vitro and metastasis in vivo of the nude mice. 24008415

2013

Entrez Id: 31
Gene Symbol: ACACA
ACACA
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.070 GeneticVariation BEFREE Despite its many drawbacks, mitotane continues to be a mainstay in the treatment of high-risk patients with ACC, especially those with recurrent or metastatic disease. 16882496

2006

Entrez Id: 31
Gene Symbol: ACACA
ACACA
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.070 Biomarker BEFREE The two novel gene sequences have been named ACC metastasis-associated RNH and ACC metastasis-associated suspected protein (GenBank # AF522024 and AF522025, respectively). 14508062

2003