Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 407021
Gene Symbol: MIR29A
MIR29A
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.100 Biomarker BEFREE Taken together, our findings reveal that miR-29a plays critical roles in the EMT and metastasis of breast cancer cells through targeting SUV420H2. 30792382

2019

Entrez Id: 407021
Gene Symbol: MIR29A
MIR29A
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.100 AlteredExpression BEFREE Additionally, a negative correlation between miR‑29a and REV3L mRNA expression levels in tumor tissues from patients with NSCLC was observed; low expression of miR‑29a and high expression of REV3L were closely associated with an advanced tumor‑node‑metastasis classification. 30535450

2019

Entrez Id: 407021
Gene Symbol: MIR29A
MIR29A
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.100 Biomarker BEFREE SIRT1 reversed partial roles of miR-29a on metastasis in cervical cancer. 31692593

2019

Entrez Id: 407021
Gene Symbol: MIR29A
MIR29A
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.100 AlteredExpression BEFREE The expression of miR‑29a and SOCS1 was found to be associated with advanced clinical stage and distant metastasis. 31364725

2019

Entrez Id: 407021
Gene Symbol: MIR29A
MIR29A
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.100 Biomarker BEFREE <b>Conclusion:</b> MiR-29a-DNMT1-SOCS1 axis plays an important role on invasion and metastasis in cervical cancer via NF-κB signaling pathway. 31038361

2019

Entrez Id: 407021
Gene Symbol: MIR29A
MIR29A
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.100 Biomarker BEFREE Integrated analyses of microRNA-29 family and the related combination biomarkers demonstrate their widespread influence on risk, recurrence, metastasis and survival outcome in colorectal cancer. 31346316

2019

Entrez Id: 407021
Gene Symbol: MIR29A
MIR29A
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.100 Biomarker BEFREE miR‑29a suppresses the growth and metastasis of hepatocellular carcinoma through IFITM3. 30272306

2018

Entrez Id: 407021
Gene Symbol: MIR29A
MIR29A
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.100 AlteredExpression BEFREE Collectively, dysregulated miR‑29a‑3p expression in gastric cancer cells was associated with malignant properties primarily relevant to migration and metastasis. 29693123

2018

Entrez Id: 407021
Gene Symbol: MIR29A
MIR29A
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.100 PosttranslationalModification BEFREE We found that miR-29a overexpression increased DNA methylation of suppressor of cytokine signaling 1 (SOCS1) promoter was associated with HCC metastasis in vitro and in vivo. 28661477

2017

Entrez Id: 407021
Gene Symbol: MIR29A
MIR29A
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.100 Biomarker BEFREE WITHDRAWN: MiR-29a Inhibits Growth and Metastasis of Melanoma A375 Cells by Directly Targeting Bmi1. 28950927

2017

Entrez Id: 407021
Gene Symbol: MIR29A
MIR29A
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.100 Biomarker BEFREE We found that miR-29a-induced cell proliferation and metastasis acceleration occurred primarily through ERK phosphorylation. 28427228

2017

Entrez Id: 407021
Gene Symbol: MIR29A
MIR29A
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.100 AlteredExpression BEFREE The results demonstrated that miR-29a was downregulated in NSCLC and the decreased expression level of miR-29a was significantly associated with advanced tumor-node-metastasis classification and metastasis. 28521487

2017

Entrez Id: 407021
Gene Symbol: MIR29A
MIR29A
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.100 Biomarker BEFREE Taken together, our results suggested that hTERT may promote GC metastasis through the hTERT-miR-29a-ITGB1 regulatory pathway. 26903137

2016

Entrez Id: 407021
Gene Symbol: MIR29A
MIR29A
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.100 GeneticVariation BEFREE Their Normfinder stability values calculated across the primary tumor and metastases subgroup indicate that miR-29a-3p can be considered as the strongest housekeeper in a cohort with mainly samples from primary tumors, whereas miR-16-5p might perform better in a metastatic sample enriched cohort. 26821018

2016

Entrez Id: 407021
Gene Symbol: MIR29A
MIR29A
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.100 Biomarker BEFREE miR-29a suppresses growth and metastasis in papillary thyroid carcinoma by targeting AKT3. 26482618

2016

Entrez Id: 407021
Gene Symbol: MIR29A
MIR29A
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.100 AlteredExpression BEFREE We found that miR-29a was up regulated in pancreatic tumor tissues and cell lines and positively correlated with metastasis. 26356262

2015

Entrez Id: 407021
Gene Symbol: MIR29A
MIR29A
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.100 Biomarker BEFREE In addition, restoration of HDAC4 attenuated miR-29a-mediated inhibition of cell proliferation and metastasis. 26441331

2015

Entrez Id: 407021
Gene Symbol: MIR29A
MIR29A
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.100 AlteredExpression BEFREE Ectopic expression of miR-21 and miR-29a promotes angiogenesis and tumor cell proliferation through the downregulation of anti-angiogenic genes such as Col4a2, Spry1 and Timp3, whereas knockdown of the miRs impedes these processes. miR-21 and miR-29a are expressed in Csf1r+ myeloid cells associated with human metastatic breast cancer, and levels of these miRs in CD115+ non-classical monocytes correlates with metastatic tumor burden in patients. 25241894

2015

Entrez Id: 407021
Gene Symbol: MIR29A
MIR29A
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.100 Biomarker BEFREE The dual role of the microRNA-29 (miR-29) family in tumor progression and metastasis in solid tumors has been reported. 24909176

2015

Entrez Id: 407021
Gene Symbol: MIR29A
MIR29A
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.100 Biomarker BEFREE Wound healing and Transwell assays revealed that miR-29a-3p suppressed tumor metastasis in GC. 25889078

2015

Entrez Id: 407021
Gene Symbol: MIR29A
MIR29A
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.100 Biomarker BEFREE However, as a tumor promoter, miR-29 mediates epithelial-mesenchymal transition (EMT) and promotes metastasis in breast cancer and colon cancer. 24573597

2014

Entrez Id: 407021
Gene Symbol: MIR29A
MIR29A
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.100 Biomarker BEFREE Increased expression of miR-29a promoted CRC metastasis by regulating MMP2/E-cad through direct targeting KLF4, which highlights the potential of the miR-29a inhibitor as a novel agent against CRC metastasis. 24281002

2014

Entrez Id: 407021
Gene Symbol: MIR29A
MIR29A
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.100 AlteredExpression BEFREE The serum levels of miR-29a and miR-29b in the patients with higher tumor grade (both P = 0.01), positive metastasis (both P = 0.006), and positive recurrence (both P = 0.006) were both markedly higher than those with lower tumor grade, negative metastasis, and negative recurrence. 25015394

2014

Entrez Id: 407021
Gene Symbol: MIR29A
MIR29A
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.100 Biomarker BEFREE The aim of this study was to investigate the functional significance of miR-29a in cervical squamous cell carcinoma (SCC) and to identify novel miR-29a-regulated cancer pathways and target genes involved in cervical SCC oncogenesis and metastasis. 24141696

2013

Entrez Id: 407021
Gene Symbol: MIR29A
MIR29A
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.100 AlteredExpression BEFREE Among these unique miRNAs, miR-140-3p, miR-29c, and miR-29a were differentially expressed in metastasis versus nonmetastatic samples and had a strong positive correlation with their DNA copy numbers and a negative correlation with the expression of their target genes. 22470160

2012