Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 57508
Gene Symbol: INTS2
INTS2
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.070 AlteredExpression BEFREE Upregulation of int-2 expression can significantly inhibit the invasion and metastasis of BcaCD885 cells. 29272002

2017

Entrez Id: 57508
Gene Symbol: INTS2
INTS2
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.070 Biomarker BEFREE Amplification of int-2 was observed in 13 of 21 cases (62%) and in all the metastatic tumors (4/4; 100%). 9316622

1997

Entrez Id: 57508
Gene Symbol: INTS2
INTS2
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.070 Biomarker BEFREE Three of 12 T1b patients with int-2 amplification died of distant organ metastasis. 8784015

1996

Entrez Id: 57508
Gene Symbol: INTS2
INTS2
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.070 Biomarker BEFREE These results suggest that int-2/hst-1 coamplification is a new biological indicator of prognosis and distant organ metastasis in patients with esophageal squamous cell carcinoma. 1997190

1991

Entrez Id: 57508
Gene Symbol: INTS2
INTS2
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.070 Biomarker BEFREE HST-1 and INT-2 genes which is a member of fibroblast growth factor gene family, are amplified in approximately 50% of primary tumors and all the metastatic tumors of esophageal carcinomas. 2098274

1990

Entrez Id: 57508
Gene Symbol: INTS2
INTS2
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.070 GeneticVariation BEFREE The HST1 and INT-2 genes, belonging to the fibroblast growth factor gene family, are coamplified in approximately 50% of primary tumors and in all the metastatic tumors of esophageal carcinoma. 2157713

1990

Entrez Id: 57508
Gene Symbol: INTS2
INTS2
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.070 GeneticVariation BEFREE Regardless of histological type, amplification of ERBB2 gene was detected in 8 metastatic tumours (25.0%), out of which three tumours had coamplification of HST1 and INT2 genes. 2386738

1990