Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6581
Gene Symbol: SLC22A3
SLC22A3
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.170 Biomarker BEFREE Targeting circFoxo3/Foxo3/EMT may provide an applicable strategy for exploring potential prognostic and therapeutic approaches for prostate cancer. 31593800

2020

Entrez Id: 6581
Gene Symbol: SLC22A3
SLC22A3
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.170 Biomarker BEFREE These results contribute to insights into the metastatic mechanisms of EMT-PCBSLCs in PCa. 31122254

2019

Entrez Id: 6581
Gene Symbol: SLC22A3
SLC22A3
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.170 Biomarker BEFREE Here we found that ASC-J9<sup>®</sup> could suppress PCa cell invasion via inducing the sumoylation of STAT3, thereby inhibiting the STAT3 phosphorylation that led to suppress the EMT-SNAIL2 signals in both PCa DU145 and PC3 AR-negative cells. 29425687

2018

Entrez Id: 6581
Gene Symbol: SLC22A3
SLC22A3
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.170 AlteredExpression BEFREE Aberrant methylation contributes to the reduced expression of OCT3 in prostate cancer. 22231567

2013

Entrez Id: 6581
Gene Symbol: SLC22A3
SLC22A3
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.170 Biomarker BEFREE Genetic and functional analyses implicate the NUDT11, HNF1B, and SLC22A3 genes in prostate cancer pathogenesis. 22730461

2012

Entrez Id: 6581
Gene Symbol: SLC22A3
SLC22A3
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.170 Biomarker BEFREE DU145 and PC3 human prostate cancer cell lines (ATCC), tumor tissue from patients with prostate cancer and normal prostate tissue were evaluated for the reprogramming factors OCT3/4 (Cell Signaling Technology), SOX2, Klf4 (Santa Cruz Biotechnology, Santa Cruz, California), Nanog (BioLegend) and c-Myc (Cell Signaling) by semiquantitative reverse transcriptase-polymerase chain reaction, histological and immunohistochemical analysis. 20303530

2010

Entrez Id: 6581
Gene Symbol: SLC22A3
SLC22A3
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.170 AlteredExpression BEFREE The objective of this study was to investigate the transcription and the protein expression of Oct 3/4 isoforms in prostate cancer and benign prostate tissue. 19274762

2009