Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4893
Gene Symbol: NRAS
NRAS
CUI: C0699790
Disease: Colon Carcinoma
Colon Carcinoma
0.040 Biomarker BEFREE In vitro, VEGF-A induced a resistance toward cetuximab cytotoxicity on three KRAS and NRAS wild type colon cancer cell lines in a VEGFR2 and Stat-3-dependent manner. 26824184

2016

Entrez Id: 4893
Gene Symbol: NRAS
NRAS
CUI: C0699790
Disease: Colon Carcinoma
Colon Carcinoma
0.040 GeneticVariation BEFREE NRAS mutations were associated with rectal cancer versus colon cancer (12.5% vs 0.6%; P < .001) and with age ≥56 years (7% vs 0.9%; P = .02). 24500602

2014

Entrez Id: 4893
Gene Symbol: NRAS
NRAS
CUI: C0699790
Disease: Colon Carcinoma
Colon Carcinoma
0.040 GeneticVariation BEFREE Female patients and older group harbored a higher KRAS mutation (P = 0.018 and P = 0.031, respectively); BRAF (V600E) mutation showed a higher frequency in colon cancer and poor differentiation tumors (P = 0.020 and P = 0.030, respectively); proximal tumors appeared a higher PIK3CA mutation (P<0.001) and distant metastatic tumors shared a higher NRAS mutation (P = 0.010). 24339949

2013

Entrez Id: 4893
Gene Symbol: NRAS
NRAS
CUI: C0699790
Disease: Colon Carcinoma
Colon Carcinoma
0.040 GeneticVariation BEFREE To further evaluate sporadic colon carcinoma risk associated with rare HRAS1 VNTR alleles, the relationship with microsatellite instability and with HRAS1 VNTR instability. 11724366

2001