Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4893
Gene Symbol: NRAS
NRAS
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.410 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016

Entrez Id: 4893
Gene Symbol: NRAS
NRAS
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.410 CausalMutation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016

Entrez Id: 4893
Gene Symbol: NRAS
NRAS
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.410 CausalMutation CLINVAR Prospective enterprise-level molecular genotyping of a cohort of cancer patients. 25157968

2015

Entrez Id: 4893
Gene Symbol: NRAS
NRAS
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.410 GeneticVariation CLINVAR Prospective enterprise-level molecular genotyping of a cohort of cancer patients. 25157968

2015

Entrez Id: 4893
Gene Symbol: NRAS
NRAS
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.410 CausalMutation CLINVAR Frequency of KRAS, BRAF, and NRAS mutations in colorectal cancer. 21305640

2011

Entrez Id: 4893
Gene Symbol: NRAS
NRAS
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.410 CausalMutation CLINVAR PIK3CA mutations frequently coexist with RAS and BRAF mutations in patients with advanced cancers. 21829508

2011

Entrez Id: 4893
Gene Symbol: NRAS
NRAS
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.410 CausalMutation CLINVAR Development of molecular biomarkers in individualized treatment of colorectal cancer. 21729679

2011

Entrez Id: 4893
Gene Symbol: NRAS
NRAS
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.410 CausalMutation CLINVAR NRAS mutations are rare in colorectal cancer. 20736745

2010

Entrez Id: 4893
Gene Symbol: NRAS
NRAS
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.410 CausalMutation CLINVAR Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: a retrospective consortium analysis. 20619739

2010

Entrez Id: 4893
Gene Symbol: NRAS
NRAS
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.410 CausalMutation CLINVAR AZD6244 (ARRY-142886), a potent inhibitor of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase 1/2 kinases: mechanism of action in vivo, pharmacokinetic/pharmacodynamic relationship, and potential for combination in preclinical models. 17699718

2007

Entrez Id: 4893
Gene Symbol: NRAS
NRAS
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.410 CausalMutation CLINVAR BRAF mutation predicts sensitivity to MEK inhibition. 16273091

2006