×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
Clinical and Genetic Implications of DNA Mismatch Repair Deficiency in Biliary Tract Cancers Associated with Lynch Syndrome.
29238914
2018
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
Comprehensive analysis of the MLH1 promoter region in 480 patients with colorectal cancer and 1150 controls reveals new variants including one with a heritable constitutional MLH1 epimutation.
29472279
2018
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
Germline Mutations in Cancer Susceptibility Genes in a Large Series of Unselected Breast Cancer Patients.
28724667
2017
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
Multigene Panel Testing Provides a New Perspective on Lynch Syndrome.
28514183
2017
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
Hereditary cancer syndromes in Latino populations: genetic characterization and surveillance guidelines.
28127413
2017
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
Cancer Susceptibility Gene Mutations in Individuals With Colorectal Cancer.
28135145
2017
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
Pancreatic Cancer in Lynch Syndrome Patients.
29151953
2017
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
Prevalence and Spectrum of Germline Cancer Susceptibility Gene Mutations Among Patients With Early-Onset Colorectal Cancer.
27978560
2017
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
A survey of the clinicopathological and molecular characteristics of patients with suspected Lynch syndrome in Latin America.
28874130
2017
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
Assessment of the InSiGHT Interpretation Criteria for the Clinical Classification of 24 MLH1 and MSH2 Gene Variants.
27629256
2017
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
Spectrum of mismatch repair gene mutations and clinical presentation of Hispanic individuals with Lynch syndrome.
28449805
2017
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
A molecular inversion probe-based next-generation sequencing panel to detect germline mutations in Chinese early-onset colorectal cancer patients.
28445943
2017
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
New EPCAM founder deletion in Polish population.
28369810
2017
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Neoplastic Syndromes, Hereditary
0.150
GeneticVariation
CLINVAR
Mismatch repair gene mutation spectrum in the Swedish Lynch syndrome population.
27601186
2016
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
Two novel sequence variants in MSH2 gene in a patient who underwent cancer genetic counseling for a very early-onset epithelial ovarian cancer.
27602174
2016
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
Systematic immunohistochemical screening for Lynch syndrome in colorectal cancer: a single centre experience of 486 patients.
27152634
2016
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing.
26681312
2016
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Neoplastic Syndromes, Hereditary
0.150
GeneticVariation
CLINVAR
Exonic Splicing Mutations Are More Prevalent than Currently Estimated and Can Be Predicted by Using In Silico Tools.
26761715
2016
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
Prevalence of Lynch syndrome in unselected patients with endometrial or ovarian cancer.
27535758
2016
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
[Founder mutation in Lynch syndrome].
27295708
2016
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
Exonic Splicing Mutations Are More Prevalent than Currently Estimated and Can Be Predicted by Using In Silico Tools.
26761715
2016
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Neoplastic Syndromes, Hereditary
0.150
GeneticVariation
CLINVAR
Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing.
26681312
2016
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Neoplastic Syndromes, Hereditary
0.150
GeneticVariation
CLINVAR
Mismatch repair deficiency concordance between primary colorectal cancer and corresponding metastasis.
26666765
2016
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
Germline mutations in PMS2 and MLH1 in individuals with solitary loss of PMS2 expression in colorectal carcinomas from the Colon Cancer Family Registry Cohort.
26895986
2016
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Neoplastic Syndromes, Hereditary
0.150
GeneticVariation
CLINVAR
Lynch syndrome mutation spectrum in New South Wales, Australia, including 55 novel mutations.
27064304
2016