×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
CausalMutation
CLINVAR
Clinical characteristics and STK11 gene mutations in Chinese children with Peutz-Jeghers syndrome.
26607058 2015
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
GeneticVariation
CLINVAR
Genetic and Clinical Analyses of Southern Chinese Children with Peutz-Jeghers Syndrome.
26225618 2015
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
CausalMutation
CLINVAR
Novel and recurrent mutations of STK11 gene in six Chinese cases with Peutz-Jeghers syndrome.
24604241 2014
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
GeneticVariation
CLINVAR
STK11 domain XI mutations: candidate genetic drivers leading to the development of dysplastic polyps in Peutz-Jeghers syndrome.
24652667 2014
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
GeneticVariation
CLINVAR
High Resolution Melting analysis as a rapid and efficient method of screening for small mutations in the STK11 gene in patients with Peutz-Jeghers syndrome.
23718779 2013
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
GeneticVariation
CLINVAR
Cancer risk associated with STK11/LKB1 germline mutations in Peutz-Jeghers syndrome patients: results of an Italian multicenter study.
23415580 2013
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
GeneticVariation
CLINVAR
Prevalence of germline PTEN, BMPR1A, SMAD4, STK11, and ENG mutations in patients with moderate-load colorectal polyps.
23399955 2013
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
CausalMutation
CLINVAR
Insights into the phosphoryl transfer catalyzed by cAMP-dependent protein kinase: an X-ray crystallographic study of complexes with various metals and peptide substrate SP20.
23672593 2013
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
GeneticVariation
CLINVAR
Predicting the functional effect of amino acid substitutions and indels.
23056405 2012
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
GeneticVariation
CLINVAR
An unusual case of sex cord tumor with annular tubules with malignant transformation in a patient with Peutz-Jeghers syndrome.
19952941 2010
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
GeneticVariation
CLINVAR
High prevalence of germline STK11 mutations in Hungarian Peutz-Jeghers Syndrome patients.
21118512 2010
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
CausalMutation
CLINVAR
High prevalence of germline STK11 mutations in Hungarian Peutz-Jeghers Syndrome patients.
21118512 2010
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
GeneticVariation
CLINVAR
Structure of the LKB1-STRAD-MO25 complex reveals an allosteric mechanism of kinase activation.
19892943 2009
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
CausalMutation
CLINVAR
Structure of the LKB1-STRAD-MO25 complex reveals an allosteric mechanism of kinase activation.
19892943 2009
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
GeneticVariation
CLINVAR
Novel mutations in the STK11 gene in Thai patients with Peutz-Jeghers syndrome.
19908348 2009
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
GeneticVariation
CLINVAR
SIRT1 modulation of the acetylation status, cytosolic localization, and activity of LKB1. Possible role in AMP-activated protein kinase activation.
18687677 2008
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
CausalMutation
CLINVAR
Molecular and clinical characteristics in 46 families affected with Peutz-Jeghers syndrome.
17404884 2007
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
CausalMutation
CLINVAR
Genetic defects underlying Peutz-Jeghers syndrome (PJS) and exclusion of the polarity-associated MARK/Par1 gene family as potential PJS candidates.
17924967 2007
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
GeneticVariation
CLINVAR
Cancer risks in LKB1 germline mutation carriers.
16407375 2006
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
GeneticVariation
CLINVAR
Frequency and spectrum of cancers in the Peutz-Jeghers syndrome.
16707622 2006
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
GeneticVariation
CLINVAR
An updated mutation spectrum in an Australian series of PJS patients provides further evidence for only one gene locus.
17026623 2006
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
CausalMutation
CLINVAR
Frequency and spectrum of cancers in the Peutz-Jeghers syndrome.
16707622 2006
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
GeneticVariation
CLINVAR
Exonic STK11 deletions are not a rare cause of Peutz-Jeghers syndrome.
16582077 2006
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
CausalMutation
CLINVAR
An updated mutation spectrum in an Australian series of PJS patients provides further evidence for only one gene locus.
17026623 2006
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
CausalMutation
CLINVAR
High proportion of large genomic STK11 deletions in Peutz-Jeghers syndrome.
16287113 2005