×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Cancer-causing mutations in the tumor suppressor PALB2 reveal a novel cancer mechanism using a hidden nuclear export signal in the WD40 repeat motif.
28158555 2017
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
PALB2 mutations in BRCA1/2-mutation negative breast and ovarian cancer patients from Poland.
28279176 2017
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Rare, protein-truncating variants in ATM , CHEK2 and PALB2 , but not XRCC2 , are associated with increased breast cancer risks.
28779002 2017
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
A high frequency of PALB2 mutations in Jamaican patients with breast cancer.
28194609 2017
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Frequency of pathogenic germline mutation in CHEK2, PALB2, MRE11, and RAD50 in patients at high risk for hereditary breast cancer.
27783279 2017
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Outcomes of retesting BRCA negative patients using multigene panels.
27878467 2017
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Germline mutations of PALB2 gene in a sequential series of Chinese patients with breast cancer.
28825143 2017
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
GeneticVariation
CLINVAR
A PALB2-interacting domain in RNF168 couples homologous recombination to DNA break-induced chromatin ubiquitylation.
28240985 2017
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Genetic Cancer Risk Assessment for Breast Cancer in Latin America.
28453507 2017
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Frequency of germline PALB2 mutations among women with epithelial ovarian cancer.
27631815 2017
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Germline Mutations in Cancer Susceptibility Genes in a Large Series of Unselected Breast Cancer Patients.
28724667 2017
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Lost in translation: returning germline genetic results in genome-scale cancer research.
28454591 2017
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Revisiting breast cancer patients who previously tested negative for BRCA mutations using a 12-gene panel.
27798748 2017
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Exome sequencing covers >98% of mutations identified on targeted next generation sequencing panels.
28152038 2017
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Pathologic findings in breast, fallopian tube, and ovary specimens in non-BRCA hereditary breast and/or ovarian cancer syndromes: a study of 18 patients with deleterious germline mutations in RAD51C, BARD1, BRIP1, PALB2, MUTYH, or CHEK2.
28709830 2017
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Germline Mutations in PALB2, BRCA1, and RAD51C, Which Regulate DNA Recombination Repair, in Patients With Gastric Cancer.
28024868 2017
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Male breast cancer in a multi-gene panel testing cohort: insights and unexpected results.
28008555 2017
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Improving performance of multigene panels for genomic analysis of cancer predisposition.
26845104 2016
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Germline Variants in Targeted Tumor Sequencing Using Matched Normal DNA.
26556299 2016
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGS.
27595995 2016
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
GeneticVariation
CLINVAR
Inherited Mutations in Women With Ovarian Carcinoma.
26720728 2016
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
A Survey of BRCA1, BRCA2, and PALB2 mutations in women with breast cancer in Trinidad and Tobago.
27469594 2016
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing.
26681312 2016
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Implementation of next-generation sequencing for molecular diagnosis of hereditary breast and ovarian cancer highlights its genetic heterogeneity.
27553368 2016
×
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Neoplastic Syndromes, Hereditary
0.100
GeneticVariation
CLINVAR
Targeted massively parallel sequencing of a panel of putative breast cancer susceptibility genes in a large cohort of multiple-case breast and ovarian cancer families.
26534844 2016