Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 998
Gene Symbol: CDC42
CDC42
CUI: C0950123
Disease: Genetic Diseases, Inborn
Genetic Diseases, Inborn
0.100 CausalMutation CLINVAR Functional Dysregulation of CDC42 Causes Diverse Developmental Phenotypes. 29394990

2018

Entrez Id: 998
Gene Symbol: CDC42
CDC42
CUI: C0950123
Disease: Genetic Diseases, Inborn
Genetic Diseases, Inborn
0.100 CausalMutation CLINVAR Macrothrombocytopenia and developmental delay with a de novo CDC42 mutation: Yet another locus for thrombocytopenia and developmental delay. 26386261

2016

Entrez Id: 998
Gene Symbol: CDC42
CDC42
CUI: C0950123
Disease: Genetic Diseases, Inborn
Genetic Diseases, Inborn
0.100 CausalMutation CLINVAR Characterization of a Cdc42 protein inhibitor and its use as a molecular probe. 23382385

2013

Entrez Id: 998
Gene Symbol: CDC42
CDC42
CUI: C0950123
Disease: Genetic Diseases, Inborn
Genetic Diseases, Inborn
0.100 CausalMutation CLINVAR Dual lipidation of the brain-specific Cdc42 isoform regulates its functional properties. 24059268

2013

Entrez Id: 998
Gene Symbol: CDC42
CDC42
CUI: C0950123
Disease: Genetic Diseases, Inborn
Genetic Diseases, Inborn
0.100 CausalMutation CLINVAR Expression analysis of Cdc42 in lung cancer and modulation of its expression by curcumin in lung cancer cell lines. 22266952

2012

Entrez Id: 998
Gene Symbol: CDC42
CDC42
CUI: C0950123
Disease: Genetic Diseases, Inborn
Genetic Diseases, Inborn
0.100 CausalMutation CLINVAR Local, persistent activation of Rho GTPases during plasticity of single dendritic spines. 21423166

2011

Entrez Id: 998
Gene Symbol: CDC42
CDC42
CUI: C0950123
Disease: Genetic Diseases, Inborn
Genetic Diseases, Inborn
0.100 CausalMutation CLINVAR Cdc42 in oncogenic transformation, invasion, and tumorigenesis. 21515363

2011

Entrez Id: 998
Gene Symbol: CDC42
CDC42
CUI: C0950123
Disease: Genetic Diseases, Inborn
Genetic Diseases, Inborn
0.100 CausalMutation CLINVAR Cdc42 and vesicle trafficking in polarized cells. 20633244

2010

Entrez Id: 998
Gene Symbol: CDC42
CDC42
CUI: C0950123
Disease: Genetic Diseases, Inborn
Genetic Diseases, Inborn
0.100 CausalMutation CLINVAR RHO GTPase signaling for axon extension: is prenylation important? 20878268

2010

Entrez Id: 998
Gene Symbol: CDC42
CDC42
CUI: C0950123
Disease: Genetic Diseases, Inborn
Genetic Diseases, Inborn
0.100 CausalMutation CLINVAR Kainic acid-induced F-344 rat model of mesial temporal lobe epilepsy: gene expression and canonical pathways. 19700661

2009

Entrez Id: 998
Gene Symbol: CDC42
CDC42
CUI: C0950123
Disease: Genetic Diseases, Inborn
Genetic Diseases, Inborn
0.100 CausalMutation CLINVAR Further delineation of deletion 1p36 syndrome in 60 patients: a recognizable phenotype and common cause of developmental delay and mental retardation. 18245432

2008

Entrez Id: 998
Gene Symbol: CDC42
CDC42
CUI: C0950123
Disease: Genetic Diseases, Inborn
Genetic Diseases, Inborn
0.100 CausalMutation CLINVAR Neural palmitoyl-proteomics reveals dynamic synaptic palmitoylation. 19092927

2008

Entrez Id: 998
Gene Symbol: CDC42
CDC42
CUI: C0950123
Disease: Genetic Diseases, Inborn
Genetic Diseases, Inborn
0.100 CausalMutation CLINVAR Molecular basis of dendritic arborization. 18511961

2008

Entrez Id: 998
Gene Symbol: CDC42
CDC42
CUI: C0950123
Disease: Genetic Diseases, Inborn
Genetic Diseases, Inborn
0.100 CausalMutation CLINVAR Monosomy 1p36 deletion syndrome. 17918734

2008

Entrez Id: 998
Gene Symbol: CDC42
CDC42
CUI: C0950123
Disease: Genetic Diseases, Inborn
Genetic Diseases, Inborn
0.100 CausalMutation CLINVAR GEFs and GAPs: critical elements in the control of small G proteins. 17540168

2007

Entrez Id: 998
Gene Symbol: CDC42
CDC42
CUI: C0950123
Disease: Genetic Diseases, Inborn
Genetic Diseases, Inborn
0.100 CausalMutation CLINVAR Involvement of E-cadherin, beta-catenin, Cdc42 and CXCR4 in the progression and prognosis of cutaneous melanoma. 17970806

2007

Entrez Id: 998
Gene Symbol: CDC42
CDC42
CUI: C0950123
Disease: Genetic Diseases, Inborn
Genetic Diseases, Inborn
0.100 CausalMutation CLINVAR Rho GTPases and actin dynamics in membrane protrusions and vesicle trafficking. 16949823

2006

Entrez Id: 998
Gene Symbol: CDC42
CDC42
CUI: C0950123
Disease: Genetic Diseases, Inborn
Genetic Diseases, Inborn
0.100 CausalMutation CLINVAR Cdc42 deficiency causes Sonic hedgehog-independent holoprosencephaly. 17050694

2006

Entrez Id: 998
Gene Symbol: CDC42
CDC42
CUI: C0950123
Disease: Genetic Diseases, Inborn
Genetic Diseases, Inborn
0.100 CausalMutation CLINVAR Rho GTPases, dendritic structure, and mental retardation. 15884002

2005

Entrez Id: 998
Gene Symbol: CDC42
CDC42
CUI: C0950123
Disease: Genetic Diseases, Inborn
Genetic Diseases, Inborn
0.100 CausalMutation CLINVAR Development of a comparative genomic hybridization microarray and demonstration of its utility with 25 well-characterized 1p36 deletions. 12915473

2004

Entrez Id: 998
Gene Symbol: CDC42
CDC42
CUI: C0950123
Disease: Genetic Diseases, Inborn
Genetic Diseases, Inborn
0.100 CausalMutation CLINVAR Overexpression of RhoA, Rac1, and Cdc42 GTPases is associated with progression in testicular cancer. 15269155

2004

Entrez Id: 998
Gene Symbol: CDC42
CDC42
CUI: C0950123
Disease: Genetic Diseases, Inborn
Genetic Diseases, Inborn
0.100 CausalMutation CLINVAR Physical map of 1p36, placement of breakpoints in monosomy 1p36, and clinical characterization of the syndrome. 12687501

2003

Entrez Id: 998
Gene Symbol: CDC42
CDC42
CUI: C0950123
Disease: Genetic Diseases, Inborn
Genetic Diseases, Inborn
0.100 CausalMutation CLINVAR Structural basis of the Rho GTPase signaling. 14561717

2003

Entrez Id: 998
Gene Symbol: CDC42
CDC42
CUI: C0950123
Disease: Genetic Diseases, Inborn
Genetic Diseases, Inborn
0.100 CausalMutation CLINVAR The evolutionary history of effectors downstream of Cdc42 and Rac. 11864373

2002

Entrez Id: 998
Gene Symbol: CDC42
CDC42
CUI: C0950123
Disease: Genetic Diseases, Inborn
Genetic Diseases, Inborn
0.100 CausalMutation CLINVAR Rho GTPases in cell biology. 12478284

2002