Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 841
Gene Symbol: CASP8
CASP8
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast
0.600 Biomarker CTD_human A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer. 29915430

2018

Entrez Id: 841
Gene Symbol: CASP8
CASP8
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast
0.600 Biomarker CTD_human A six-nucleotide insertion-deletion polymorphism in the CASP8 promoter is associated with susceptibility to multiple cancers. 17450141

2007

Entrez Id: 841
Gene Symbol: CASP8
CASP8
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast
0.600 Biomarker CTD_human We found evidence of an association with breast cancer for CASP8 D302H (with odds ratios (OR) of 0.89 (95% confidence interval (c.i.): 0.85-0.94) and 0.74 (95% c.i. 17293864

2007

Entrez Id: 841
Gene Symbol: CASP8
CASP8
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast
0.600 Biomarker CTD_human The reproducible, dose-dependent association of CASP8 D302H with breast cancer indicates the potential importance of inherited variation in the apoptosis pathway in breast cancer susceptibility. 15601643

2004

Entrez Id: 841
Gene Symbol: CASP8
CASP8
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast
0.600 CausalMutation CGI