Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.400 Biomarker PSYGENET Ghrelin effects expression of several genes associated with depression-like behavior. 25286107

2015

Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.400 Biomarker PSYGENET TNF-α -308G/A and IL-8 -251T/A were significantly associated with AD and IL-1β +3953C/T with late-life depression, while the significance of these associations was lost after Bonferroni correction. 25315113

2015

Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.400 Biomarker PSYGENET Previously, we reported that IL-1 receptor antagonist (IL-1Ra) knockout (KO) mice, which lacked IL-1Ra molecules that antagonize the IL-1 receptor, showed anti-depression-like behavior via adrenergic modulation at the age of 8 weeks. 26002078

2015

Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.400 Biomarker PSYGENET We demonstrated that prenatal stress leads to depression-like behavior, decreased IGF-1, increased IL-1β, TNF-α and IFN-γ release and disturbed SOCS-1, SOCS-2 and SOCS-3 expression in the hippocampus and frontal cortex of adult offspring. 25151093

2014

Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.400 Biomarker PSYGENET Role of interleukin-1β in hypoxia-induced depression of glutamate uptake in retinal Müller cells. 24218043

2014