Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6647
Gene Symbol: SOD1
SOD1
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.600 Biomarker PSYGENET The changes in mitochondrial activity in brain and reduced expressions of superoxide dismutase (SOD1, SOD2), mitofusin (Mfn1, Mfn2) as well as brain-derived neurotrophic factor (BDNF) suggest that both CORT and CUMS may impair mitochondrial function and/or expressions of mitofusion and antioxidant enzymes that, in turn, may increase oxidative stress and reduce energy production in brain with depression-like behaviors. 22244747

2012

Entrez Id: 6647
Gene Symbol: SOD1
SOD1
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.600 Biomarker CTD_human Lipid peroxidation and antioxidant protection in patients during acute depressive episodes and in remission after fluoxetine treatment. 19605942

2009

Entrez Id: 6647
Gene Symbol: SOD1
SOD1
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.600 Biomarker PSYGENET GABAergic functions, expressed in extracellular paired-pulse depression, and in IPSCs recorded in dentate granular cells were enhanced in Tg-SOD-1 mice. 10594078

2000