Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2078
Gene Symbol: ERG
ERG
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.400 Biomarker CTD_human Taken together, our work shows that overexpressed ERG co-opts master transcription factors to deploy a unique cis-regulatory landscape, inducing a druggable dependency on NOTCH signaling in T2E-positive prostate tumors. 28783165

2017

Entrez Id: 2078
Gene Symbol: ERG
ERG
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.400 Biomarker CTD_human TMPRSS2-ERG (T2E) structural rearrangements typify ∼50% of prostate tumors and result in overexpression of the ERG transcription factor. 28783165

2017

Entrez Id: 2078
Gene Symbol: ERG
ERG
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.400 Biomarker CTD_human Integrative molecular profiling of routine clinical prostate cancer specimens. 25735316

2016

Entrez Id: 2078
Gene Symbol: ERG
ERG
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.400 Biomarker CTD_human BET bromodomain-mediated interaction between ERG and BRD4 promotes prostate cancer cell invasion. 27223260

2016

Entrez Id: 2078
Gene Symbol: ERG
ERG
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.400 Biomarker CTD_human An Interaction with Ewing's Sarcoma Breakpoint Protein EWS Defines a Specific Oncogenic Mechanism of ETS Factors Rearranged in Prostate Cancer. 27783944

2016

Entrez Id: 2078
Gene Symbol: ERG
ERG
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.400 Biomarker CTD_human Aberrant ERG expression cooperates with loss of PTEN to promote cancer progression in the prostate. 19396168

2009

Entrez Id: 2078
Gene Symbol: ERG
ERG
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.400 Biomarker CTD_human Defining the molecular action of HDAC inhibitors and synergism with androgen deprivation in ERG-positive prostate cancer. 18798265

2009

Entrez Id: 2078
Gene Symbol: ERG
ERG
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.400 Biomarker CTD_human Integrative molecular concept modeling of prostate cancer progression. 17173048

2007