Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 9863
Gene Symbol: MAGI2
MAGI2
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.850 Biomarker CTD_human One of the rare CNVs found in SZ cohorts is the duplication of Synaptic Scaffolding Molecule (S-SCAM, also called MAGI-2), which encodes a postsynaptic scaffolding protein controlling synaptic AMPA receptor levels, and thus the strength of excitatory synaptic transmission. 25653350

2015

Entrez Id: 9863
Gene Symbol: MAGI2
MAGI2
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.850 Biomarker PSYGENET One of the rare CNVs found in SZ cohorts is the duplication of Synaptic Scaffolding Molecule (S-SCAM, also called MAGI-2), which encodes a postsynaptic scaffolding protein controlling synaptic AMPA receptor levels, and thus the strength of excitatory synaptic transmission. 25653350

2015

Entrez Id: 9863
Gene Symbol: MAGI2
MAGI2
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.850 Biomarker PSYGENET In conclusion, although we could not detect strong genetic evidence for association of common variants in MAGI2 and increased schizophrenia risk in a Japanese population, these SNPs may increase risk of cognitive impairment in schizophrenic patients. 22649501

2012

Entrez Id: 9863
Gene Symbol: MAGI2
MAGI2
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.850 Biomarker PSYGENET Because earlier work had identified a CNV in the close relative MAGI2 in SZ, the study was extended to include MAGI2. 22381734

2012