Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2100
Gene Symbol: ESR2
ESR2
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.400 Biomarker CTD_human We identify two independent susceptibility loci for prostate cancer at 11p15.4 (rs12791447, P=3.59 × 10(-8); PPFIBP2) and 14q23.2 (rs58262369, P=6.05 × 10(-10); ESR2). 26443449

2016

Entrez Id: 2100
Gene Symbol: ESR2
ESR2
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.400 Therapeutic CTD_human We identify two independent susceptibility loci for prostate cancer at 11p15.4 (rs12791447, P=3.59 × 10(-8); PPFIBP2) and 14q23.2 (rs58262369, P=6.05 × 10(-10); ESR2). 26443449

2016

Entrez Id: 2100
Gene Symbol: ESR2
ESR2
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.400 Biomarker CTD_human Regulation and expression of human CYP7B1 in prostate: overexpression of CYP7B1 during progression of prostatic adenocarcinoma. 17639508

2007

Entrez Id: 2100
Gene Symbol: ESR2
ESR2
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.400 Biomarker CTD_human Apigenin suppresses cancer cell growth through ERbeta. 17132221

2007

Entrez Id: 2100
Gene Symbol: ESR2
ESR2
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.400 Therapeutic CTD_human Regulation and expression of human CYP7B1 in prostate: overexpression of CYP7B1 during progression of prostatic adenocarcinoma. 17639508

2007

Entrez Id: 2100
Gene Symbol: ESR2
ESR2
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.400 Therapeutic CTD_human Apigenin suppresses cancer cell growth through ERbeta. 17132221

2007

Entrez Id: 2100
Gene Symbol: ESR2
ESR2
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.400 Therapeutic CTD_human Our study provides strong evidence that high intake of phytoestrogens substantially reduce prostate cancer risk among men with specific polymorphic variation in the promoter region of the estrogen receptor-beta gene. 16921512

2006

Entrez Id: 2100
Gene Symbol: ESR2
ESR2
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.400 Therapeutic CTD_human Interactions between phytoestrogen intake and estrogen receptor-beta SNPs on prostate cancer risk were evaluated considering both multiplicative and additive effect scales. 16921512

2006

Entrez Id: 2100
Gene Symbol: ESR2
ESR2
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.400 Biomarker CTD_human Our study provides strong evidence that high intake of phytoestrogens substantially reduce prostate cancer risk among men with specific polymorphic variation in the promoter region of the estrogen receptor-beta gene. 16921512

2006

Entrez Id: 2100
Gene Symbol: ESR2
ESR2
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.400 Biomarker CTD_human Interactions between phytoestrogen intake and estrogen receptor-beta SNPs on prostate cancer risk were evaluated considering both multiplicative and additive effect scales. 16921512

2006

Entrez Id: 2100
Gene Symbol: ESR2
ESR2
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.400 Therapeutic CTD_human [Implications of estrogens and their receptors for the development and progression of prostate cancer]. 16220300

2006

Entrez Id: 2100
Gene Symbol: ESR2
ESR2
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.400 Biomarker CTD_human Dietary intake of phytoestrogens, estrogen receptor-beta polymorphisms and the risk of prostate cancer. 16921512

2006

Entrez Id: 2100
Gene Symbol: ESR2
ESR2
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.400 Biomarker CTD_human [Implications of estrogens and their receptors for the development and progression of prostate cancer]. 16220300

2006

Entrez Id: 2100
Gene Symbol: ESR2
ESR2
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.400 Therapeutic CTD_human Dietary intake of phytoestrogens, estrogen receptor-beta polymorphisms and the risk of prostate cancer. 16921512

2006

Entrez Id: 2100
Gene Symbol: ESR2
ESR2
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.400 Therapeutic CTD_human The evolving role of estrogen therapy in prostate cancer. 15046698

2004

Entrez Id: 2100
Gene Symbol: ESR2
ESR2
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.400 Biomarker CTD_human The evolving role of estrogen therapy in prostate cancer. 15046698

2004