Source: CURATED

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6716
Gene Symbol: SRD5A2
SRD5A2
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		0.400 Biomarker CTD_human For prostate cancer, the best two-gene interaction included genotypes SRD5A2 V89L GG and AKR1C3 Q5H CC with OR 1.30, 95% CI 1.01-1.66. 18306354

2008
Entrez Id: 6716
Gene Symbol: SRD5A2
SRD5A2
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		0.400 Biomarker CTD_human [Dutasteride in the treatment of hormone refractory prostate cancer]. 18500220

2008
Entrez Id: 6716
Gene Symbol: SRD5A2
SRD5A2
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		0.400 Biomarker CTD_human In Caucasians, the HSD3B2 (TG)n,(TA)n,(CA)n intron 3 length polymorphism is associated with both prostate cancer risk and aggressiveness and the SRD5A2 V89L polymorphism may modify the risk conferred by this polymorphism. 17823934

2007
Entrez Id: 6716
Gene Symbol: SRD5A2
SRD5A2
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		0.400 Biomarker CTD_human Our study provides evidence that the SRD5A2 A49T A variant is associated with an increased risk of prostate cancer, lower levels of circulating 3alpha-diolG and decreased risk of baldness. 17136762

2007
Entrez Id: 6716
Gene Symbol: SRD5A2
SRD5A2
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		0.400 Biomarker CTD_human Systematic replication study of reported genetic associations in prostate cancer: Strong support for genetic variation in the androgen pathway. 16998812

2006