DisGeNET - a database of gene-disease associations

Source: CURATED

Disease: Hereditary Diffuse Gastric Cancer ×

Gene: CTNNA1 ×

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Gene

Disease

Score _gda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

Entrez Id:	1495
Gene Symbol:	CTNNA1

CTNNA1

CUI:	C1708349
Disease:	Hereditary Diffuse Gastric Cancer

Hereditary Diffuse Gastric Cancer

0.340

GeneticVariation

ORPHANET

In HDGC families lacking CDH1 mutations, testing of CTNNA1 and other tumor suppressor genes should be considered.

26182300

2015

Entrez Id:	1495
Gene Symbol:	CTNNA1

CTNNA1

CUI:	C1708349
Disease:	Hereditary Diffuse Gastric Cancer

Hereditary Diffuse Gastric Cancer

0.340

GeneticVariation

ORPHANET

Recognition of and recent issues in hereditary diffuse gastric cancer.

26049741

2015

Entrez Id:	1495
Gene Symbol:	CTNNA1

CTNNA1

CUI:	C1708349
Disease:	Hereditary Diffuse Gastric Cancer

Hereditary Diffuse Gastric Cancer

0.340

GeneticVariation

ORPHANET

An α-E-catenin (CTNNA1) mutation in hereditary diffuse gastric cancer.

23208944

2013