Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer
0.800 Biomarker CTD_human Whole-genome sequencing and comprehensive molecular profiling identify new driver mutations in gastric cancer. 24816253

2014

Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer
0.800 Biomarker CTD_human Chronic aspirin use suppresses CDH1 methylation in human gastric mucosa. 19184424

2010

Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer
0.800 Biomarker CTD_human As the finding of pathogenic CDH1 mutations is useful for management of HDGC families, screening for deletions should be offered to at-risk families. 19168852

2009

Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer
0.800 GermlineCausalMutation ORPHANET As the finding of pathogenic CDH1 mutations is useful for management of HDGC families, screening for deletions should be offered to at-risk families. 19168852

2009

Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer
0.800 Biomarker CLINGEN As the finding of pathogenic CDH1 mutations is useful for management of HDGC families, screening for deletions should be offered to at-risk families. 19168852

2009

Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer
0.800 GeneticVariation UNIPROT However, germline CDH1 mutations have not been described in patients with LBC in non-HDGC families. 17660459

2007

Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer
0.800 Biomarker CLINGEN Cleft lip/palate and CDH1/E-cadherin mutations in families with hereditary diffuse gastric cancer. 15831593

2006

Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer
0.800 Biomarker CLINGEN Direct evidence of E-cadherin mutations triggering tumorigenesis has come from the finding of inactivating germline mutations of the gene (CDH1) in hereditary diffuse gastric cancer (HDGC). 12588804

2003

Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer
0.800 Biomarker CTD_human Direct evidence of E-cadherin mutations triggering tumorigenesis has come from the finding of inactivating germline mutations of the gene (CDH1) in hereditary diffuse gastric cancer (HDGC). 12588804

2003

Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer
0.800 Biomarker CLINGEN E-cadherin germline missense mutations and cell phenotype: evidence for the independence of cell invasion on the motile capabilities of the cells. 14500541

2003

Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer
0.800 GeneticVariation UNIPROT E-cadherin gene variants in gastric cancer families whose probands are diagnosed with diffuse gastric cancer. 12216071

2002

Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer
0.800 GeneticVariation UNIPROT We screened five Korean familial gastric cancer patients to investigate germline mutations of the E-cadherin gene. 10319582

1999

Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer
0.800 Biomarker CTD_human We have confirmed that germline mutations in the CDH1 gene cause familial gastric cancer in non-Maori populations. 10072428

1999

Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer
0.800 Biomarker CLINGEN We have confirmed that germline mutations in the CDH1 gene cause familial gastric cancer in non-Maori populations. 10072428

1999

Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer
0.800 Biomarker CLINGEN A causal role for E-cadherin in the transition from adenoma to carcinoma. 9515965

1998

Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer
0.800 Biomarker CTD_human E-cadherin germline mutations in familial gastric cancer. 9537325

1998

Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer
0.800 Biomarker CLINGEN E-cadherin germline mutations in familial gastric cancer. 9537325

1998

Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer
0.800 Biomarker CLINGEN From cadherins to catenins: cytoplasmic protein interactions and regulation of cell adhesion. 8236461

1993

Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer
0.800 Biomarker CLINGEN Expression of E- and P-cadherin in gastric carcinomas. 2009537

1991

Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer
0.800 Biomarker CLINGEN Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role. 2070412

1991

Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer
0.800 Biomarker GENOMICS_ENGLAND