Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3784
Gene Symbol: KCNQ1
KCNQ1
Diabetes Mellitus, Non-Insulin-Dependent
0.500 GeneticVariation GWASCAT Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease. 28869590

2017

Entrez Id: 3784
Gene Symbol: KCNQ1
KCNQ1
Diabetes Mellitus, Non-Insulin-Dependent
0.500 GeneticVariation GWASCAT Genetics of Type 2 Diabetes in U.S. Hispanic/Latino Individuals: Results From the Hispanic Community Health Study/Study of Latinos (HCHS/SOL). 28254843

2017

Entrez Id: 3784
Gene Symbol: KCNQ1
KCNQ1
Diabetes Mellitus, Non-Insulin-Dependent
0.500 GeneticVariation GWASCAT Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes. 26818947

2016

Entrez Id: 3784
Gene Symbol: KCNQ1
KCNQ1
Diabetes Mellitus, Non-Insulin-Dependent
0.500 GeneticVariation GWASCAT Meta-analysis of genome-wide association studies in African Americans provides insights into the genetic architecture of type 2 diabetes. 25102180

2015

Entrez Id: 3784
Gene Symbol: KCNQ1
KCNQ1
Diabetes Mellitus, Non-Insulin-Dependent
0.500 GeneticVariation GWASCAT A genome-wide association study in American Indians implicates DNER as a susceptibility locus for type 2 diabetes. 24101674

2014

Entrez Id: 3784
Gene Symbol: KCNQ1
KCNQ1
Diabetes Mellitus, Non-Insulin-Dependent
0.500 GeneticVariation GWASCAT Genome-wide association study identifies three novel loci for type 2 diabetes. 23945395

2014

Entrez Id: 3784
Gene Symbol: KCNQ1
KCNQ1
Diabetes Mellitus, Non-Insulin-Dependent
0.500 GeneticVariation GWASCAT Sequence variants in SLC16A11 are a common risk factor for type 2 diabetes in Mexico. 24390345

2014

Entrez Id: 3784
Gene Symbol: KCNQ1
KCNQ1
Diabetes Mellitus, Non-Insulin-Dependent
0.500 GeneticVariation GWASCAT Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. 24509480

2014

Entrez Id: 3784
Gene Symbol: KCNQ1
KCNQ1
Diabetes Mellitus, Non-Insulin-Dependent
0.500 GeneticVariation GWASCAT Besides confirming seven established T2D loci (CDKAL1, CDKN2A/B, KCNQ1, CDC123, GLIS3, HNF1B, and DUSP9) at genome-wide significance, we identified two novel T2D loci, including G-protein-coupled receptor kinase 5 (GRK5) (rs10886471: P = 7.1 × 10(-9)) and RASGRP1 (rs7403531: P = 3.9 × 10(-9)), of which the association signal at GRK5 seems to be specific to East Asians. 22961080

2013

Entrez Id: 3784
Gene Symbol: KCNQ1
KCNQ1
Diabetes Mellitus, Non-Insulin-Dependent
0.500 GeneticVariation GWASCAT Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. 22885922

2012

Entrez Id: 3784
Gene Symbol: KCNQ1
KCNQ1
Diabetes Mellitus, Non-Insulin-Dependent
0.500 GeneticVariation GWASCAT We confirmed the associations of KCNQ1 and C2CD4A/B with T2D, with the latter for the first time being examined in Han Chinese. 21799836

2011

Entrez Id: 3784
Gene Symbol: KCNQ1
KCNQ1
Diabetes Mellitus, Non-Insulin-Dependent
0.500 GeneticVariation GWASCAT We also confirmed that variants in KCNQ1 were associated with T2D risk, with the strongest signal at rs2237895 (P = 9.65x10(-10); OR = 1.29, 95% CI = 1.19-1.40). 20174558

2010

Entrez Id: 3784
Gene Symbol: KCNQ1
KCNQ1
Diabetes Mellitus, Non-Insulin-Dependent
0.500 GeneticVariation GWASCAT By identifying two novel genetic susceptibility loci in a Han Chinese population and confirming the involvement of KCNQ1, which was previously reported to be associated with T2D in Japanese and European descent populations, our results may lead to a better understanding of differences in the molecular pathogenesis of T2D among various populations. 20174558

2010

Entrez Id: 3784
Gene Symbol: KCNQ1
KCNQ1
Diabetes Mellitus, Non-Insulin-Dependent
0.500 GeneticVariation GWASCAT Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. 20581827

2010

Entrez Id: 3784
Gene Symbol: KCNQ1
KCNQ1
Diabetes Mellitus, Non-Insulin-Dependent
0.500 GeneticVariation GWASCAT Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus. 18711367

2009

Entrez Id: 3784
Gene Symbol: KCNQ1
KCNQ1
Diabetes Mellitus, Non-Insulin-Dependent
0.500 GeneticVariation GWASCAT The association of KCNQ1 with type 2 diabetes was replicated in populations of Korean, Chinese and European ancestry as well as in two independent Japanese populations, and meta-analysis with a total of 19,930 individuals (9,569 cases and 10,361 controls) yielded a P value of 1.7 x 10(-42) (OR = 1.40; 95% CI = 1.34-1.47) for rs2237892. 18711367

2009

Entrez Id: 3784
Gene Symbol: KCNQ1
KCNQ1
Diabetes Mellitus, Non-Insulin-Dependent
0.500 GeneticVariation GWASCAT SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations. 18711366

2009

Entrez Id: 3784
Gene Symbol: KCNQ1
KCNQ1
Diabetes Mellitus, Non-Insulin-Dependent
0.500 GeneticVariation GWASCAT We conducted a genome-wide association study using 207,097 SNP markers in Japanese individuals with type 2 diabetes and unrelated controls, and identified KCNQ1 (potassium voltage-gated channel, KQT-like subfamily, member 1) to be a strong candidate for conferring susceptibility to type 2 diabetes. 18711366

2009

Entrez Id: 3784
Gene Symbol: KCNQ1
KCNQ1
Diabetes Mellitus, Non-Insulin-Dependent
0.500 GeneticVariation GWASCAT Confirmation of multiple risk Loci and genetic impacts by a genome-wide association study of type 2 diabetes in the Japanese population. 19401414

2009