×
Entrez Id:
7490
Gene Symbol:
WT1
WT1
Denys-Drash Syndrome
1.000
GeneticVariation
UNIPROT
A novel mutation of WT1 exon 9 in a patient with Denys-Drash syndrome and pyloric stenosis.
15349765
2004
×
Entrez Id:
7490
Gene Symbol:
WT1
WT1
Denys-Drash Syndrome
1.000
GeneticVariation
UNIPROT
Novel WT1 mutation (C388Y) in a female child with Denys-Drash syndrome.
11519891
2001
×
Entrez Id:
7490
Gene Symbol:
WT1
WT1
Denys-Drash Syndrome
1.000
GeneticVariation
UNIPROT
Novel WT1 exon 9 mutation (D396Y) in a patient with early onset Denys Drash syndrome.
10738002
2000
×
Entrez Id:
7490
Gene Symbol:
WT1
WT1
Denys-Drash Syndrome
1.000
GeneticVariation
UNIPROT
Constitutional WT1 correlate with clinical features in children with progressive nephropathy.
11182928
2000
×
Entrez Id:
7490
Gene Symbol:
WT1
WT1
Denys-Drash Syndrome
1.000
GeneticVariation
UNIPROT
A novel missense mutation of the Wt1 gene causing Denys-Drash syndrome with exceptionally mild renal manifestations.
10799199
2000
×
Entrez Id:
7490
Gene Symbol:
WT1
WT1
Denys-Drash Syndrome
1.000
GeneticVariation
UNIPROT
Identification of constitutional WT1 mutations, in patients with isolated diffuse mesangial sclerosis, and analysis of genotype/phenotype correlations by use of a computerized mutation database.
9529364
1998
×
Entrez Id:
7490
Gene Symbol:
WT1
WT1
Denys-Drash Syndrome
1.000
GeneticVariation
UNIPROT
Do intronic mutations affecting splicing of WT1 exon 9 cause Frasier syndrome?
9475094
1998
×
Entrez Id:
7490
Gene Symbol:
WT1
WT1
Denys-Drash Syndrome
1.000
GeneticVariation
UNIPROT
A novel mutation H373Y in the Wilms' tumor suppressor gene, WT1, associated with Denys-Drash syndrome.
8956030
1997
×
Entrez Id:
7490
Gene Symbol:
WT1
WT1
Denys-Drash Syndrome
1.000
GeneticVariation
UNIPROT
Denys-Drash syndrome was suspected and molecular analysis of the WT1 gene was performed, although no Wilms' tumor was identified.
8741319
1996
×
Entrez Id:
7490
Gene Symbol:
WT1
WT1
Denys-Drash Syndrome
1.000
GeneticVariation
UNIPROT
Analysis of exons 2-10 of the WT1 gene in constitutional DNA from five patients with DDS was carried out using the polymerase chain reaction (PCR) and direct DNA sequencing.
8112732
1994
×
Entrez Id:
7490
Gene Symbol:
WT1
WT1
Denys-Drash Syndrome
1.000
GeneticVariation
UNIPROT
Molecular analysis of two Japanese cases of Denys-Drash syndrome.
8295405
1993
×
Entrez Id:
7490
Gene Symbol:
WT1
WT1
Denys-Drash Syndrome
1.000
GeneticVariation
UNIPROT
Evidence that WT1 mutations in Denys-Drash syndrome patients may act in a dominant-negative fashion.
8388765
1993
×
Entrez Id:
7490
Gene Symbol:
WT1
WT1
Denys-Drash Syndrome
1.000
GeneticVariation
UNIPROT
However, in addition to the 12 patients, three DDS patients were also analysed using SSCP, and in all three cases heterozygous WT1 mutations were found which would be predicted to disrupt the DNA binding activity of WT1 protein.
8411073
1993
×
Entrez Id:
7490
Gene Symbol:
WT1
WT1
Denys-Drash Syndrome
1.000
GeneticVariation
UNIPROT
A novel zinc finger mutation in a patient with Denys-Drash syndrome.
8111391
1993
×
Entrez Id:
7490
Gene Symbol:
WT1
WT1
Denys-Drash Syndrome
1.000
GeneticVariation
UNIPROT
Germline intronic and exonic mutations in the Wilms' tumour gene (WT1) affecting urogenital development.
1302008
1992
×
Entrez Id:
7490
Gene Symbol:
WT1
WT1
Denys-Drash Syndrome
1.000
GeneticVariation
UNIPROT
Constitutional mutations in the WT1 gene in patients with Denys-Drash syndrome .
1338906
1992
×
Entrez Id:
7490
Gene Symbol:
WT1
WT1
Denys-Drash Syndrome
1.000
GeneticVariation
UNIPROT
In ten independent cases of Denys-Drash syndrome , point mutations in the zinc finger domains of one WT1 gene copy were found.
1655284
1991