Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7490
Gene Symbol: WT1
WT1
CUI: C0950121
Disease: Denys-Drash Syndrome
Denys-Drash Syndrome
1.000 GeneticVariation UNIPROT A novel mutation of WT1 exon 9 in a patient with Denys-Drash syndrome and pyloric stenosis. 15349765

2004

Entrez Id: 7490
Gene Symbol: WT1
WT1
CUI: C0950121
Disease: Denys-Drash Syndrome
Denys-Drash Syndrome
1.000 GeneticVariation UNIPROT Novel WT1 mutation (C388Y) in a female child with Denys-Drash syndrome. 11519891

2001

Entrez Id: 7490
Gene Symbol: WT1
WT1
CUI: C0950121
Disease: Denys-Drash Syndrome
Denys-Drash Syndrome
1.000 GeneticVariation UNIPROT Novel WT1 exon 9 mutation (D396Y) in a patient with early onset Denys Drash syndrome. 10738002

2000

Entrez Id: 7490
Gene Symbol: WT1
WT1
CUI: C0950121
Disease: Denys-Drash Syndrome
Denys-Drash Syndrome
1.000 GeneticVariation UNIPROT Constitutional WT1 correlate with clinical features in children with progressive nephropathy. 11182928

2000

Entrez Id: 7490
Gene Symbol: WT1
WT1
CUI: C0950121
Disease: Denys-Drash Syndrome
Denys-Drash Syndrome
1.000 GeneticVariation UNIPROT A novel missense mutation of the Wt1 gene causing Denys-Drash syndrome with exceptionally mild renal manifestations. 10799199

2000

Entrez Id: 7490
Gene Symbol: WT1
WT1
CUI: C0950121
Disease: Denys-Drash Syndrome
Denys-Drash Syndrome
1.000 GeneticVariation UNIPROT Identification of constitutional WT1 mutations, in patients with isolated diffuse mesangial sclerosis, and analysis of genotype/phenotype correlations by use of a computerized mutation database. 9529364

1998

Entrez Id: 7490
Gene Symbol: WT1
WT1
CUI: C0950121
Disease: Denys-Drash Syndrome
Denys-Drash Syndrome
1.000 GeneticVariation UNIPROT Do intronic mutations affecting splicing of WT1 exon 9 cause Frasier syndrome? 9475094

1998

Entrez Id: 7490
Gene Symbol: WT1
WT1
CUI: C0950121
Disease: Denys-Drash Syndrome
Denys-Drash Syndrome
1.000 GeneticVariation UNIPROT A novel mutation H373Y in the Wilms' tumor suppressor gene, WT1, associated with Denys-Drash syndrome. 8956030

1997

Entrez Id: 7490
Gene Symbol: WT1
WT1
CUI: C0950121
Disease: Denys-Drash Syndrome
Denys-Drash Syndrome
1.000 GeneticVariation UNIPROT Denys-Drash syndrome was suspected and molecular analysis of the WT1 gene was performed, although no Wilms' tumor was identified. 8741319

1996

Entrez Id: 7490
Gene Symbol: WT1
WT1
CUI: C0950121
Disease: Denys-Drash Syndrome
Denys-Drash Syndrome
1.000 GeneticVariation UNIPROT Analysis of exons 2-10 of the WT1 gene in constitutional DNA from five patients with DDS was carried out using the polymerase chain reaction (PCR) and direct DNA sequencing. 8112732

1994

Entrez Id: 7490
Gene Symbol: WT1
WT1
CUI: C0950121
Disease: Denys-Drash Syndrome
Denys-Drash Syndrome
1.000 GeneticVariation UNIPROT Molecular analysis of two Japanese cases of Denys-Drash syndrome. 8295405

1993

Entrez Id: 7490
Gene Symbol: WT1
WT1
CUI: C0950121
Disease: Denys-Drash Syndrome
Denys-Drash Syndrome
1.000 GeneticVariation UNIPROT Evidence that WT1 mutations in Denys-Drash syndrome patients may act in a dominant-negative fashion. 8388765

1993

Entrez Id: 7490
Gene Symbol: WT1
WT1
CUI: C0950121
Disease: Denys-Drash Syndrome
Denys-Drash Syndrome
1.000 GeneticVariation UNIPROT However, in addition to the 12 patients, three DDS patients were also analysed using SSCP, and in all three cases heterozygous WT1 mutations were found which would be predicted to disrupt the DNA binding activity of WT1 protein. 8411073

1993

Entrez Id: 7490
Gene Symbol: WT1
WT1
CUI: C0950121
Disease: Denys-Drash Syndrome
Denys-Drash Syndrome
1.000 GeneticVariation UNIPROT A novel zinc finger mutation in a patient with Denys-Drash syndrome. 8111391

1993

Entrez Id: 7490
Gene Symbol: WT1
WT1
CUI: C0950121
Disease: Denys-Drash Syndrome
Denys-Drash Syndrome
1.000 GeneticVariation UNIPROT Germline intronic and exonic mutations in the Wilms' tumour gene (WT1) affecting urogenital development. 1302008

1992

Entrez Id: 7490
Gene Symbol: WT1
WT1
CUI: C0950121
Disease: Denys-Drash Syndrome
Denys-Drash Syndrome
1.000 GeneticVariation UNIPROT Constitutional mutations in the WT1 gene in patients with Denys-Drash syndrome. 1338906

1992

Entrez Id: 7490
Gene Symbol: WT1
WT1
CUI: C0950121
Disease: Denys-Drash Syndrome
Denys-Drash Syndrome
1.000 GeneticVariation UNIPROT In ten independent cases of Denys-Drash syndrome, point mutations in the zinc finger domains of one WT1 gene copy were found. 1655284

1991