Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs266729
rs266729
Diabetes Mellitus, Non-Insulin-Dependent
0.100 GeneticVariation BEFREE Sources of control populations were the cause of between-study heterogeneity; nonetheless, there was no publication bias among studies.The G allele of rs266729 in adiponectin gene increases the risk of T2DM through an additive genetic model with an effect of 1.13 (1.06, 1.19). 29381968

2017

dbSNP: rs266729
rs266729
Diabetes Mellitus, Non-Insulin-Dependent
0.100 GeneticVariation BEFREE However, G vs C allele of -11377C>G (rs266729) might be a risk factor for type 2 diabetes. 21638131

2011

dbSNP: rs266729
rs266729
Diabetes Mellitus, Non-Insulin-Dependent
0.100 GeneticVariation BEFREE To derive a more precise estimation, we performed a meta-analysis to assess the association between five AdipoQ polymorphisms [-11426A > G (rs16861194), -11391G > A (rs17300539), -11377C > G (rs266729), +45T > G (rs2241766) and +276G > T (rs1501299)], and T2DM risk. 23653335

2013

dbSNP: rs266729
rs266729
Diabetes Mellitus, Non-Insulin-Dependent
0.100 GeneticVariation BEFREE On the contrary, -11377C/G (rs266729) was associated with type 2 diabetes in the obese group only (OR=2.45, 95%CI: 1.13-5.31, P=0.02), and 59% risk of diabesity could be attributed to that. 19359061

2009

dbSNP: rs266729
rs266729
Diabetes Mellitus, Non-Insulin-Dependent
0.100 GeneticVariation BEFREE T2D was significantly associated with promoter rs266729, rs17300539, rs1884613, rs2144908, and rs4810424, and the association of T2D risk were affected by study population, diagnostic criteria, and genotype methods. 30860284

2019

dbSNP: rs266729
rs266729
Diabetes Mellitus, Non-Insulin-Dependent
0.100 GeneticVariation BEFREE A significant interaction was observed between two SNPs rs13306519 in LEPR and rs266729 in ADIPOQ for T2DM (P_int = 0.012, OR_int = 2.67) and hypertension (P_int = 0.0041, OR_int = 2.23). 24414038

2014

dbSNP: rs266729
rs266729
Diabetes Mellitus, Non-Insulin-Dependent
0.100 GeneticVariation BEFREE However, we found an effect modification of obesity on the association between the ADIPOQ rs266729 SNP and total cholesterol (P = 0.00068) only in obese participants after adjusting for age, gender, BMI, and T2D status. 27388775

2016

dbSNP: rs266729
rs266729
Diabetes Mellitus, Non-Insulin-Dependent
0.100 GeneticVariation BEFREE The rs266729 C allele and the rare minor alleles of rs2241766 and rs2082940 were associated with an increased adjusted hazard ratio of developing T2DM. 21219602

2011

dbSNP: rs266729
rs266729
Diabetes Mellitus, Non-Insulin-Dependent
0.100 GeneticVariation BEFREE Adiponectin rs2241766T/G and rs17300593G/A rather than rs1501299G/T and rs266729C/G polymorphisms were associated with the risk of DN in T2DM, especially in the Caucasian population. 24825737

2015

dbSNP: rs266729
rs266729
Diabetes Mellitus, Non-Insulin-Dependent
0.100 GeneticVariation BEFREE Adiponectin gene polymorphism rs266729 is involved in the pathogenesis of T2DM. 26051417

2015

dbSNP: rs266729
rs266729
Diabetes Mellitus, Non-Insulin-Dependent
0.100 GeneticVariation BEFREE Varied association of ADIPOQ genotypes with T2DM was seen according to the genetic model used: rs17300539 and rs266729</span> were significantly associated with T2DM under the three models, while rs16861194 was association with T2DM under additive and dominant models, and rs822396, rs2241766, and rs1063538 were associated with T2DM under the dominant models only. 22497971

2012

dbSNP: rs266729
rs266729
Diabetes Mellitus, Non-Insulin-Dependent
0.100 GeneticVariation BEFREE The results of this study indicate that the use of 8 genetic polymorphisms associated with carbohydrate and lipid metabolism and type 2 diabetes [<i>PTGS2</i> (<i>COX2</i>) rs6681231, <i>FADS1</i> rs174550, <i>HNF1B</i> rs4430796, <i>ADIPOQ</i> rs266729, <i>IL18</i> rs187238, <i>CCL2</i> rs1024611, <i>HHEX</i> rs5015480 and <i>CDKN2A/2B</i> rs10811661] together with clinical risk factors (BMI and age) may significantly improve the prediction of GDM. 31299695

2019

dbSNP: rs266729
rs266729
Diabetes Mellitus, Non-Insulin-Dependent
0.100 GeneticVariation BEFREE Of the 8 variants, four SNPs namely, +276 G/T (rs1501299), -4522 C/T (rs822393), -11365 C/G (rs266729), and +712 G/A (rs3774261) were significantly associated with T2DM in our study population. 24055485

2013

dbSNP: rs266729
rs266729
Diabetes Mellitus, Non-Insulin-Dependent
0.100 GeneticVariation BEFREE Association of the ADIPOQ rs17360539 and rs266729 polymorphisms with type 2 diabetes: a meta-analysis. 20580771

2010

dbSNP: rs2241766
rs2241766
Diabetes Mellitus, Non-Insulin-Dependent
0.100 GeneticVariation BEFREE A case-control study was conducted to assess the association of rs2241766 and rs822395 SNPs of adiponectin gene (ADIPOQ) with T2DM in Iraqi population. 29627525

2018

dbSNP: rs2241766
rs2241766
Diabetes Mellitus, Non-Insulin-Dependent
0.100 GeneticVariation BEFREE Further, the ADIPOQ g. + 45 T > G and TNF-α g. - 308 G > A polymorphisms jointly give 1.45-fold risk towards T2D. 24655058

2014

dbSNP: rs2241766
rs2241766
Diabetes Mellitus, Non-Insulin-Dependent
0.100 GeneticVariation BEFREE To derive a more precise estimation, we performed a meta-analysis to assess the association between five AdipoQ polymorphisms [-11426A > G (rs16861194), -11391G > A (rs17300539), -11377C > G (rs266729), +45T > G (rs2241766) and +276G > T (rs1501299)], and T2DM risk. 23653335

2013

dbSNP: rs2241766
rs2241766
Diabetes Mellitus, Non-Insulin-Dependent
0.100 GeneticVariation BEFREE Adiponectin rs2241766T/G and rs17300593G/A rather than rs1501299G/T and rs266729C/G polymorphisms were associated with the risk of DN in T2DM, especially in the Caucasian population. 24825737

2015

dbSNP: rs2241766
rs2241766
Diabetes Mellitus, Non-Insulin-Dependent
0.100 GeneticVariation BEFREE The presence of +45T>G (rs2241766), +276G>T (rs1501299) and -11391G>A (rs17300539) do not appear to influence the development of type 2 diabetes. 21638131

2011

dbSNP: rs2241766
rs2241766
Diabetes Mellitus, Non-Insulin-Dependent
0.100 GeneticVariation BEFREE Varied association of ADIPOQ genotypes with T2DM was seen according to the genetic model used: rs17300539 and rs266729 were significantly associated with T2DM under the three models, while rs16861194 was association with T2DM under additive and dominant models, and rs822396, rs2241766, and rs1063538 were associated with T2DM under the dominant models only. 22497971

2012

dbSNP: rs2241766
rs2241766
Diabetes Mellitus, Non-Insulin-Dependent
0.100 GeneticVariation BEFREE The T45G and G276T of the adiponectin gene may not be an important determinant of Type 2 diabetes or insulin resistance in Korean subjects. 15842511

2005

dbSNP: rs2241766
rs2241766
Diabetes Mellitus, Non-Insulin-Dependent
0.100 GeneticVariation BEFREE Together, our data support that the rs2241766 and rs1501299 polymorphisms within the ADIPOQ gene confer genetic susceptibility for type 2 diabetes, especially in the Chinese Han population. 25135112

2014

dbSNP: rs2241766
rs2241766
Diabetes Mellitus, Non-Insulin-Dependent
0.100 GeneticVariation BEFREE In this case-control study, the associations of rs2241766 T/G of ADIPOQ, rs9289231 T/G of KALRN, and rs9939609 A/T of FTO polymorphisms with genetic susceptibility to CAD in type 2 diabetic (T2D) patients were investigated. 27218147

2016

dbSNP: rs2241766
rs2241766
Diabetes Mellitus, Non-Insulin-Dependent
0.100 GeneticVariation BEFREE The adiponectin gene 45T/G mutation may be an important determinant of type 2 diabetes in the Iranian population. 22187345

2012

dbSNP: rs2241766
rs2241766
Diabetes Mellitus, Non-Insulin-Dependent
0.100 GeneticVariation BEFREE Adiponectin gene polymorphism 45T>G is associated with carotid artery plaques in patients with type 2 diabetes mellitus. 18191060

2008